6973-05-3 Usage
General Description
2-Acetamido-5-aminobenzenesulfonic acid is a chemical compound that belongs to the class of sulfonic acids. It is also known as N-Acetyl-5-Aminosalicylic Acid (5-ASA) and is used as a pharmaceutical ingredient in the treatment of inflammatory bowel diseases such as ulcerative colitis and Crohn's disease. It is a derivative of the anti-inflammatory drug mesalazine and works by reducing inflammation in the colon. Additionally, 2-Acetamido-5-aminobenzenesulfonic acid has been studied for its potential use in treating other inflammatory conditions, such as rheumatoid arthritis and non-alcoholic fatty liver disease. It is important to handle this chemical with care, as it can be hazardous if not used properly.
Check Digit Verification of cas no
The CAS Registry Mumber 6973-05-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,9,7 and 3 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6973-05:
(6*6)+(5*9)+(4*7)+(3*3)+(2*0)+(1*5)=123
123 % 10 = 3
So 6973-05-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H10N2O4S/c1-5(11)10-7-3-2-6(9)4-8(7)15(12,13)14/h2-4H,9H2,1H3,(H,10,11)(H,12,13,14)
6973-05-3Relevant articles and documents
Nitric Oxide Catalysis of Diazene E / Z Isomerization
Bohle, D. Scott,Rosadiuk, Kristopher A.
supporting information, p. 7145 - 7151 (2015/08/11)
Nitric oxide is an efficient catalyst for the cis-trans (E/Z) isomerization of diazenes. We compare the effect of room temperature solutions bearing low concentrations of nitric oxide, nitrogen dioxide, or oxygen on the rate of cis-trans isomerization, CTI, of the alkene bond in stilbene and on the azo double bond in azobenzene, as well as in four azo derivatives as measured by UV-vis spectroscopy. These rate enhancements can be as large as 3 orders of magnitude for azobenzene in solution. A mechanism is proposed where catalysis is promoted by the interaction of the nitric oxide with the diazene nitrogen lone pairs. Density functional theory, B3LYP/6-311++g suggests that the binding of NO to the diazene should be weak and reversible but that its NO adduct has an E/Z isomerization barrier of 7.5 kcal/mol.
