6973-05-3 Usage
Uses
Used in Pharmaceutical Industry:
2-Acetamido-5-aminobenzenesulfonic acid is used as an active pharmaceutical ingredient for the treatment of inflammatory bowel diseases such as ulcerative colitis and Crohn's disease. It functions by reducing inflammation in the colon, providing relief to patients suffering from these conditions.
Additionally, 2-Acetamido-5-aminobenzenesulfonic acid is being studied for its potential use in treating other inflammatory conditions. It has shown promise in managing symptoms of rheumatoid arthritis, a chronic autoimmune disorder that causes inflammation in the joints, and non-alcoholic fatty liver disease, a condition characterized by excessive fat accumulation in the liver.
It is crucial to handle 2-Acetamido-5-aminobenzenesulfonic acid with care, as it can be hazardous if not used properly. Proper safety measures should be taken during its production, storage, and application to ensure the well-being of individuals involved in its use.
Check Digit Verification of cas no
The CAS Registry Mumber 6973-05-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,9,7 and 3 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6973-05:
(6*6)+(5*9)+(4*7)+(3*3)+(2*0)+(1*5)=123
123 % 10 = 3
So 6973-05-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H10N2O4S/c1-5(11)10-7-3-2-6(9)4-8(7)15(12,13)14/h2-4H,9H2,1H3,(H,10,11)(H,12,13,14)
6973-05-3Relevant academic research and scientific papers
Nitric Oxide Catalysis of Diazene E / Z Isomerization
Bohle, D. Scott,Rosadiuk, Kristopher A.
supporting information, p. 7145 - 7151 (2015/08/11)
Nitric oxide is an efficient catalyst for the cis-trans (E/Z) isomerization of diazenes. We compare the effect of room temperature solutions bearing low concentrations of nitric oxide, nitrogen dioxide, or oxygen on the rate of cis-trans isomerization, CTI, of the alkene bond in stilbene and on the azo double bond in azobenzene, as well as in four azo derivatives as measured by UV-vis spectroscopy. These rate enhancements can be as large as 3 orders of magnitude for azobenzene in solution. A mechanism is proposed where catalysis is promoted by the interaction of the nitric oxide with the diazene nitrogen lone pairs. Density functional theory, B3LYP/6-311++g suggests that the binding of NO to the diazene should be weak and reversible but that its NO adduct has an E/Z isomerization barrier of 7.5 kcal/mol.
