697304-21-5

Upstream product

• 697304-66-8 ethyl (2R,3S)-2-amino-3-(1H-indol-3-yl)butanoate 
• 74124-79-1 di(succinimido) carbonate 
• 10272-49-8 4-phenylpiperidine hydrochloride 
• 697306-96-0 ethyl (2R,3S)-2-amino-3-(1H-indol-3-yl)butanoate methanesulfonate 
• 530-62-1 1,1'-carbonyldiimidazole 

Downstream Products

• 697304-01-1 (2R,3S)-3-(1H-indol-3-yl)-2-[(4-phenylpiperidine-1-carbonyl)amino]butyric acid 

Relevant academic research and scientific papers

A practical synthesis of enantiopure β-methyltryptophan ethyl ester for a preparation of diabetes drug

A practical synthesis of (2R,3S)- and (2S,3R)-β-methyltryptophan ethyl ester (β-MeTrp-OEt) has been developed. Racemic threo-β-MeTrp-OEt was diastereoselectively prepared via crystallization-induced diastereomer transformation (CIDT) of the α-nitro equiva

AMINE COMPOUNDS

The present invention provide a compound of the formula:wherein ring A represents an aromatic ring optionally having substituents; B, Y and Ya are the same or different and each represents a bond, etc.; R1 and R2 are the same or different and each represents a hydrogen atom, etc.; R3 represents a hydrogen atom, etc.; R4 and R5 are the same or different and each represents a hydrogen, etc.; R6 represents an indolyl group optionally having substituents; and Z and Za are the same or different and each represents a hydrogen atom, etc.; or a salt thereof or a prodrug thereof, having a somatostatin receptor binding inhibition activity and is useful for preventing and/or treating diseases associated with somatostatin.