697307-70-3Relevant academic research and scientific papers
A practical synthesis of enantiopure β-methyltryptophan ethyl ester for a preparation of diabetes drug
Sawai, Yasuhiro,Mizuno, Masahiro,Ito, Tatsuya,Kawakami, Jun-ichi,Yamano, Mitsuhisa
experimental part, p. 7122 - 7128 (2009/12/06)
A practical synthesis of (2R,3S)- and (2S,3R)-β-methyltryptophan ethyl ester (β-MeTrp-OEt) has been developed. Racemic threo-β-MeTrp-OEt was diastereoselectively prepared via crystallization-induced diastereomer transformation (CIDT) of the α-nitro equiva
AMINE COMPOUNDS
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Page 297-298, (2010/02/07)
The present invention provide a compound of the formula:wherein ring A represents an aromatic ring optionally having substituents; B, Y and Ya are the same or different and each represents a bond, etc.; R1 and R2 are the same or different and each represents a hydrogen atom, etc.; R3 represents a hydrogen atom, etc.; R4 and R5 are the same or different and each represents a hydrogen, etc.; R6 represents an indolyl group optionally having substituents; and Z and Za are the same or different and each represents a hydrogen atom, etc.; or a salt thereof or a prodrug thereof, having a somatostatin receptor binding inhibition activity and is useful for preventing and/or treating diseases associated with somatostatin.
