69751-40-2

Upstream product

• 140-29-4 phenylacetonitrile 
• 109-04-6 2-bromo-pyridine 
• 5005-36-7 phenyl-pyridin-2-yl-acetonitrile 
• 95898-97-8 2-phenyl-2-(pyridin-2-yl)ethan-1-amine 
• 108-24-7 acetic anhydride 

Downstream Products

• 1581709-80-9 N-methyl-N-[2-phenyl-2-(pyridin-2-yl)ethyl]acetamide 

Relevant academic research and scientific papers

Copper-catalyzed α-methylenation of benzylpyridines using dimethylacetamide as one-carbon source

The direct α-methylenation of benzylpyridines was achieved using N,N-dimethylacetamide (DMA) as a one-carbon source under copper catalysis. An intermediary species was detected at an early stage, and a possible mechanism was proposed. Additionally, α-oxygenation and dimerization of benzylpyridines could also be performed efficiently.