6976-78-9

Basic information

• Product Name: ethyl 2-butylamino-2-phenyl-acetate
• Synonyms: ethyl 2-butylamino-2-phenyl-acetate
• CAS NO: 6976-78-9
• Molecular Formula: C14H21NO2
• Molecular Weight: 0
• Mol File: 6976-78-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 319.3°C at 760 mmHg
• Flash Point: 146.9°C
• Appearance: /
• Density: 1.004g/cm³
• Vapor Pressure: 0.000342mmHg at 25°C
• Refractive Index: 1.5
• CAS DataBase Reference: ethyl 2-butylamino-2-phenyl-acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-butylamino-2-phenyl-acetate(6976-78-9)
• EPA Substance Registry System: ethyl 2-butylamino-2-phenyl-acetate(6976-78-9)

Safety Data

• Hazardous Substances Data: 6976-78-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H21NO2/c1-3-5-11-15-13(14(16)17-4-2)12-9-7-6-8-10-12/h6-10,13,15H,3-5,11H2,1-2H3

Upstream product

• 1603-79-8 phenylglyoxylic acid ethyl ester 
• 109-72-8 n-butyllithium 

Relevant articles and documents

Tandem N, N-Dialkylation Reaction of N-Trimethylsilyl α-Iminoesters Utilizing an Umpolung Reaction and Characteristics of the Silyl Substituent: Synthesis of Pyrrolidine, Piperidine, and Iminodiacetate

Umpolung reactions of N-trimethylsilyl α-iminoester with organometallics gave directly N-alkylaminoesters in high yields without the need for removing a protecting group at the nitrogen atom. Efficient syntheses of pyrrolidines, piperidines, and iminodiacetate derivatives were also developed via tandem N,N- or N,C-dialkylation reactions utilizing characteristics of the silyl substituent. Furthermore, under the influence of silica gel, the addition of an enolate to the imino nitrogen proceeded to give an iminodiacetate derivative.