697738-98-0

Basic information

• Product Name: 5-aMino-1-Methyl-1,2,3,4-tetrahydroquinolin-2-one
• Synonyms: 5-aMino-1-Methyl-1,2,3,4-tetrahydroquinolin-2-one;5-AMino-1-Methyl-3,4-dihydroquinolin-2(1H)-one;5-amino-3,4-dihydro-1-methyl-2(1H)-Quinolinone;5-Amino-1-methyl-3,4-dihydro-1H-quinolin-2-one
• CAS NO: 697738-98-0
• Molecular Formula: C10H12N2O
• Molecular Weight: 176.21508
• Mol File: 697738-98-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-aMino-1-Methyl-1,2,3,4-tetrahydroquinolin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-aMino-1-Methyl-1,2,3,4-tetrahydroquinolin-2-one(697738-98-0)
• EPA Substance Registry System: 5-aMino-1-Methyl-1,2,3,4-tetrahydroquinolin-2-one(697738-98-0)

Safety Data

• Hazardous Substances Data: 697738-98-0(Hazardous Substances Data)

Usage

General Description

5-Amino-1-Methyl-1,2,3,4-tetrahydroquinolin-2-one is a chemical compound with the molecular formula C10H12N2O. It is a tetrahydroquinoline derivative, which has potential applications in the pharmaceutical industry as it exhibits biological activity. The compound is known for its ability to inhibit certain enzymes and receptors, making it a potential candidate for drug development. Additionally, it has been studied for its potential neuroprotective and anticancer properties. 5-Amino-1-Methyl-1,2,3,4-tetrahydroquinolin-2-one is a compound of interest for further research and development in the field of medicinal chemistry.

Upstream product

• 697738-97-9 1‐methyl‐5‐nitroquinolin‐2‐one 

Relevant articles and documents

AMINO-HETEROCYCLES AS VR-1 ANTAGONISTS FOR TREATING PAIN

the present invention provides a compound of formula (I): wherein V represents NR5, O, S, SO or S(O)2; W and X each independently represent CH or N; Y represents N, CH or C-Ar2, with the proviso that at least one, but no more than two, of W, X and Y are N; Z represents CH or C-Ar2, with the proviso that when Y is N or CH then Z is C-Ar2, and with the further proviso that when Y is C-Ar2 then Z is CH; Ar1 represents a fused 9 or 10 membered heterobicyclic ring system containing one, two, three or four heteroatoms selected from nitrogen, oxygen and sulfur, wherein at least one of the rings in said ring system is aromatic; Ar2 represents an aromatic ring selected from phenyl, pyridyl, pyrimidinyl and pyridazinyl which is optionally fused and substituted; R1 represents halogen, hydroxy, oxo, C1-6alkyl, C2-6alkenyl, C2-6alkynyl, haloC1-6alkyl, hydroxyC1-6alkyl, C1-6alkoxy, haloC1-6alkoxy, hydroxyC1-6alkoxy, C3-7cycloalkyl, C3-7cycloalkoxy, C3-5cycloalkylC1-4alkyl, cyano, nitro, SR6, SOR6, SO2R6, COR6, NR3COR6, CONR3R4, NR3SO2R6, SO2NR3R4, -(CH2)mcarboxy, esterified -(CH2)mcarboxy or -(CH2)mNR3R4; R2 represents hydrogen, halogen, hydroxy, C1-6alkyl, haloC1-6alkyl, C3-7cycloalkyl, C1-6alkoxy, haloC1-6alkoxy, unsubstituted phenyl or phenyl substituted with one or two groups selected from halogen, C1-6alkyl, haloC1-6alkyl, C3-7cycloalkyl, C1-6alkoxy or haloC1-6alkoxy; R3 and R4 are each independently hydrogen, C1-6alkyl, C2-6alkenyl, C2-6alkynyl, C3-7cycloalkyl or fluoroC1-6alkyl; or R3 and R4 and the nitrogen atom to which they are attached together form a heteroaliphatic ring of 4 to 7 ring atoms, optionally substituted by one or two groups selected from hydroxy or C1-4alkoxy, which ring may optionally contain as one of the said ring atoms an oxygen or a sulfur atom, S(O), S(O)2, or NR5; R5 represents hydrogen, C1-4alkyl, hydroxyC1-4alkyl or C1-4alkoxyC1-4alkyl; R6 represents hydrogen, C1-6alkyl, fluoroC1-6alkyl, C3-7cycloalkyl, unsubstituted phenyl, or phenyl substituted with one or two groups selected from halogen, C1-6alkyl, haloC1-6alkyl, C3-7cycloalkyl, C1-6alkoxy or haloC1-6alkoxy; m is either zero or an integer from 1 to 4; n is either zero or an integer from 1 to 3; or a pharmaceutically acceptable salt, N-oxide or a prodrug thereof; a pharmaceutical composition comprising it; its use in methods of treatment; use of it for the manufacture of a medicament for treating VR-1 related conditions such as those in which pain and/or inflammation predominate; and methods of treatment using it.