697759-12-9Relevant academic research and scientific papers
The triflic acid-mediated cyclisation of N-benzylcinnamanilides
King, Frank D.,Caddick, Stephen
, p. 8592 - 8601 (2013/09/12)
N-Benzylcinnamanilides cyclise with triflic acid to form 1-benzyl-4-aryl-2,4-dihydro-1H-quinolin-2-ones and 2,5-diaryl-benzazepin-3-ones. The product ratio is determined by the preferred orientation of the amide and by the electronics of the substituents. With ortho-substituted anilides, N-debenzylation also occurs to give 4-aryl-2,4-dihydro-1H-quinoline-2-ones.
The triflic acid-mediated cyclisation of N-benzyl-cinnamamides
King, Frank D.,Caddick, Stephen
, p. 487 - 491 (2013/07/27)
N-Benzyl-cinnamamides cyclise with triflic acid to form 5-aryl-benzazepinones and/or cinnamamides.
Rhodium-catalyzed domino conjugate addition-cyclization reactions for the synthesis of a variety of N- and O-heterocycles: Arylboroxines as effective carbon nucleophiles
Park, Ja Ock,Youn, So Won
supporting information; scheme or table, p. 2258 - 2261 (2010/07/17)
Facile and efficient Rh(I)-catalyzed domino conjugate addition-cyclization reactions of olefins bearing two electrophilic sites and a pendant nucleophile with organoboroxines have been developed to afford a variety of N- and O-heterocycles, such as 3,4-dihydroquinolin-2(1H)-ones, 3,4-dihydrocoumarins, and pyrrolidin-2-ones, which constitute important motifs in biologically active natural and synthetic organic compounds.
