69776-54-1Relevant academic research and scientific papers
Antianaphylactic agents. 1. 2-(Acylamino)oxazoles
Ross,Harrison,Jolley,Neville,Todd,Verge,Dawson,Sweatman
, p. 412 - 417 (2007/10/08)
The synthesis and biological properties of 35 2-(acylamino)oxazoles are described. The majority of the compounds inhibit the release of slow-reacting substance of anaphylaxis (SRS-A) in vitro from sensitized guinea pig chopped lung. In addition, several of the compounds inhibited the release of SRS-A from passively sensitized human chopped lung and protected guinea pigs from the effects of anaphylaxis in a modified Herxheimer test.
