6979-01-7 Usage
General Description
1-(2-Hydrazinylethyl)piperidine, also known as NEPA, is a chemical compound with the molecular formula C8H18N2. It is a novel antiemetic drug that is used to prevent chemotherapy-induced nausea and vomiting. NEPA is a combination of netupitant, a neurokinin-1 receptor antagonist, and palonosetron, a serotonin 5-HT3 receptor antagonist. This dual mechanism of action makes NEPA highly effective in preventing nausea and vomiting associated with chemotherapy. NEPA is well-tolerated and has shown to be more effective than traditional antiemetic drugs, making it a promising option for cancer patients undergoing chemotherapy.
Check Digit Verification of cas no
The CAS Registry Mumber 6979-01-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,9,7 and 9 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 6979-01:
(6*6)+(5*9)+(4*7)+(3*9)+(2*0)+(1*1)=137
137 % 10 = 7
So 6979-01-7 is a valid CAS Registry Number.
6979-01-7Relevant articles and documents
2-Pyrazolin-5-ones bearing a basic dialkylaminoalkyl substituent at the N1-position: Preparation and NMR spectroscopic investigations
Wolf, Barbara M.T.,Eller, Gernot A.,Holzer, Wolfgang
experimental part, p. 2035 - 2042 (2009/04/06)
2-Pyrazolin-5-ones (= tautomers to 5-hydroxypyrazols) bearing dialkylaminoyalkyl substituents at the ring nitrogen atom N-1 are prepared from the corresponding hydrazines and beta-ketoesters. Detailed NMR spectroscopic investigations (1H,