69791-24-8Relevant academic research and scientific papers
New thiobarbituric acid scaffold-based small molecules: Synthesis, cytotoxicity, 2D-QSAR, pharmacophore modelling and in-silico ADME screening
El-Zahabi, Heba S.A.,Khalifa, Maha M.A.,Gado, Yomna M.H.,Farrag, Amel M.,Elaasser, Mahmoud M.,Safwat, Nesreen A.,AbdelRaouf, Reham R.,Arafa, Reem K.
, p. 124 - 136 (2019)
A series of twenty five new thiobarbituric acid derivatives, viz. 3a-h, 4–7, 8a-c, 9, 10a-c, 11 and 12a-d, were designed and synthesized as potential cytotoxic agents. In-vitro screening of the new compounds against the three human cancer cell lines Caco-
