698372-46-2Relevant academic research and scientific papers
N-Heterocyclic Carbene Catalyzed Stereoselective Synthesis of 2-Nitro-thiogalactosides
Chen, Jie,Gou, Bo-Bo,Hu, Yu-Long,Liu, Jia-Lin,Wang, Jiao,Zhao, Ming,Zhou, Ling
, p. 3451 - 3461 (2019)
A highly selective NHC-catalyzed Michael addition of alkanethiols or thiophenol to 2-nitro- d -galactal compounds for the synthesis of 2-nitro-thiogalactoside derivatives has been developed for the first time. A wide variety of 1,2- cis -2-nitro-thiogalactosides can be prepared in good to excellent yields and high to excellent α-selectivities.
An efficient route toward 2-amino-β-D-galacto-and -glucopyranosides via stereoselective michael-type addition of 2-nitroglycals
Xue, Weihua,Sun, Jiansong,Yu, Biao
experimental part, p. 5079 - 5082 (2009/10/17)
(Chemical Equation Presented) Under the catalysis of DMAP or PPY in CH 2Cl2, the Michael-type addition of nucleophiles to 2-nitrogalactal or 2-nitroglucal leads in excellent yields and stereoselectivity to the corresponding β-galacto
2-Nitro thioglycoside donors: Versatile precursors of β-D-glycosides of aminosugars
Barroca, Nadine,Schmidt, Richard R.
, p. 1551 - 1554 (2007/10/03)
2-Nitro thioglycosides can be prepared by the Michael addition of thiophenol to 2-nitroglycal derivatives. NIS/TMSOTf activation of these 2-nitro thioglycosides, in the presence of alcohols, rapidly and cleanly led to the desired glycosides in good yield
