6987-22-0Relevant academic research and scientific papers
Synthesis of difluoromethyl and deuterium-labeled difluoromethyl thioethers from aliphatic electrophiles
Ding, Tianqi,Jiang, Lvqi,Yi, Wenbin
, p. 3995 - 3998 (2020/04/17)
A one-pot difluoromethylthiolation of alkyl electrophiles with thiourea and diethyl bromodifluoromethylphosphonate is described. The transition-metal-free approach, readily available reagents, and mild conditions provide a practical way for the synthesis of difluoromethyl thioethers. By changing the "H" source to the most commonly used "D" sources CD3OD and D2O, this strategy enables efficient synthesis of SCF2D-substituted molecules in good yields with high levels of D incorporation.
Water-Soluble Nanoparticle Receptors Supramolecularly Coded for Acidic Peptides
Fa, Shixin,Zhao, Yan
supporting information, p. 150 - 158 (2017/12/13)
Sequence-specific recognition of peptides is of enormous importance to many chemical and biological applications, but has been difficult to achieve due to the minute differences in the side chains of amino acids. Acidic peptides are known to play importan
ANTIMICROBIAL POLYMERIC PARTICLES
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Paragraph 261-266, (2017/10/31)
Disclosed methyl styrene farmin compounds, and crosslinked polymeric backbones comprising same. Further disclosed microsized and nanosized polymeric particles comprising polyisothiouronium methylstyrene (PITMS) and/or poly(methyl styrene farmin) or a derivative thereof, and uses thereof in, for example, reducing or preventing growth of microorganisms.
Reversible crosslinking of polymers bearing pendant or terminal thiol groups prepared by nitroxide-mediated radical polymerization
Braslau, Rebecca,Rivera III, Frank,Tansakul, Chittreeya
, p. 624 - 633 (2013/05/08)
Monomers or N-alkoxyamine initiators containing protected thiol groups are utilized to prepare polymers via nitroxide-mediated radical polymerization. Following thiol deprotection, the macromolecular properties of these polymers are manipulated, by adjusting the redox conditions to either form or cleave disulfide bonds, or irreversibly cap free thiols by the rapid addition to a maleimide Michael acceptor. Formation of disulfide bonds under dilute conditions results in intramolecular disulfide formation, resulting in internal polymer collapse. Alternatively, disulfide formation under high concentration results in intermolecular crosslinking of polymers to form networked macromolecular assemblies.
White light emission transparent polymer nanocomposites with novel poly(p-phenylene vinylene) derivatives and surface functionalized CdSe/ZnS NCs
Liu, Bingxin,Lü, Xiaodan,Wang, Chunyu,Tong, Cuiyan,He, Yao,Lü, Changli
, p. 192 - 200 (2013/10/21)
A series of new polymers with conjugated poly(p-phenylene vinylene) units and non-conjugated poly(p-xylylene) units containing vinyl and carboxyl groups were synthesized. The monodisperse CdSe/ZnS nanocrystals with a red light emission were prepared by us
A "catch-react-release" method for the flow synthesis of 2-aminopyrimidines and preparation of the imatinib base
Ingham, Richard J.,Riva, Elena,Nikbin, Nikzad,Baxendale, Ian R.,Ley, Steven V.
supporting information; experimental part, p. 3920 - 3923 (2012/09/22)
The development of a monolith-supported synthetic procedure is reported, taking advantage of flow processing and the superior flow characteristics of monolithic reagents over gel-phase beads, to allow facile access to an important family of 2-aminopyrimidine derivatives. The process has been successfully applied to a key precursor on route to Imatinib (Ar = 3-pyridyl, R1 = 2-methyl-5-nitrobenzyl, R2 = H).
