69875-94-1Relevant academic research and scientific papers
Secondary amines: Synthesis and effect of length of spacer linking two phenyl rings on biological activity
Rani, Neeraj,Sharma,Kaul,Manrao
experimental part, p. 1041 - 1044 (2009/12/24)
N-Benzyl benzylamines (1a-11a) and N-benzyl anilines (1b-11b) were synthesized by sodium borohydride reduction of aldimines of benzylamine and aniline respectively. The products were characterized on the basis of elemental analysis and spectral studies and screened for antifungal potential against four fungi and evaluated for nematicidal activity against two nematodes. The former compounds were found to be more effective as compared to the latter thus indicating an enhancement of biological activity due to introduction of an extra methylene group between two phenyl rings of aromatic secondary amines.
