6988-55-2Relevant articles and documents
C21 steroidal glycosides from Cynanchum stauntonii induce apoptosis in HepG2 cells
Che, Chun-Tao,Ma, Lin,Wang, Lei,Wei, Yu-Jian,Wu, Zheng-Feng,Ye, Wen-Cai,Yin, Zhi-Qi,Yu, Shu-Le,Zhang, Jian,Zhang, Qing-Wen,Zhao, Ming
, p. 55 - 61 (2020/07/03)
Two new (1–2) and three known (3–5) C21 steroidal glycosides were isolated from Cynanchum stauntonii. Their structures were elucidated on the basis of 1D and 2D-NMR spectroscopic data as well as HRTOFMS analysis. The cytotoxicity of the compoun
Two new glycosides and one new neolignan from the roots of Cynanchum stauntonii
Yu, Jin-Qian,Zhao, Lei
, p. 355 - 359 (2015/08/19)
Three new compounds including one C21-steroidal glycoside, one methylglycoside, and one neolignan, named as Deoxyamplexicogenin A-3-O-yl-4-O-(4-O-α-L-cymaropyranosoyl-β-D-digitoxopyranosoyl)-β-D-canaropyranoside (1), Methyl-O-α-L-cymaropyranosoyl-(1 → 4)-β-D-digitoxopyranoside (2), and (+)-(7S, 8R, 7′E)-5-hydroxy-3, 5′-dimethoxy-4′, 7-epoxy-8, 3′-neolign-7′-ene-9, 9′-diol 9′-ethyl ether (3), respectively, were isolated from the roots of Cynanchum stauntonii. The structure elucidations were achieved by in-depth spectroscopic examination, mainly including the experiments and analyses of multiple 1D- and 2D-NMR and HRESIMS and CD analysis and qualitative chemical tests. Cytotoxicity activities of compounds 1-3 were evaluated against five tumor cell lines (HCT-8, Bel-7402, BGC-823, A549, and A2780) in cell based assays where they were found to be inactive.
Chemical constituents from the roots of Periploca sepium with insecticidal activity
Li, Yan,Zeng, Xin-Nian,Wang, Wen-Zhong,Luo, Cai-Hong,Yan, Qin,Tian, Meng
, p. 811 - 816 (2012/11/13)
Five compounds were isolated from the root powder of Periploca sepium. By mainly HR-ESI-MS, 1H, 13C, and 2D NMR spectral data, they were characterized as periplocoside X (1), oligasaccharide A (2), periplocoside A (3), periplocoside E (4), and periplocoside N (5), respectively. Compounds 1-5 were found to possess insecticidal activities against the red imported fire ant. Among the compounds, periplocoside X showed significant activity with LD50 values of 748.99, 116.62, 2169.58, and 3079.33mg/l against soldiers, workers, males, and alate females of red imported fire ant, respectively.