69888-36-4Relevant academic research and scientific papers
Facile approaches toward the synthesis of 6H-isoindolo[2,1-α]indol-6-ones via palladium-catalyzed carbonylation with carbon monoxide
Han, Qingshuai,Fu, Shurong,Zhang, Xiaofeng,Lin, Shen,Huang, Qiufeng
supporting information, p. 4165 - 4169 (2016/08/24)
Two facile methods for the preparation of 6H-isoindolo[2,1-α]indol-6-ones were developed. In the first protocol, 6H-isoindolo[2,1-α]indol-6-ones were prepared from 2-(2-iodophenyl)-1H-indoles via palladium-catalyzed intramolecular aminocarbonylation. The
Palladium-Catalyzed Carbonylative Synthesis of N -Benzoylindoles with Mo(CO)6 as the Carbon Monoxide Source
Wu, Xiao-Feng,Oschatz, Stefan,Sharif, Muhammad,Langer, Peter
, p. 2641 - 2646 (2015/09/01)
A mild and carbon monoxide gas-free palladium-catalyzed aminocarbonylation of indole has been developed for the synthesis of N-benzoylindoles. This method uses Mo(CO)6 as a convenient CO-precursor and BuPAd2 as the ligand. A number o
A palladium-catalyzed carbonylation approach to acid chloride synthesis
Quesnel, Jeffrey S.,Arndtsen, Bruce A.
supporting information, p. 16841 - 16844 (2013/12/04)
We describe a new approach to acid chloride synthesis via the palladium-catalyzed carbonylation of aryl iodides. The combination of sterically encumbered phosphines (PtBu3) and CO coordination has been found to facilitate the rapid carbonylation of aryl iodides into acid chlorides via reductive elimination from (tBu3P)(CO) Pd(COAr)Cl. The formation of acid chlorides can also be exploited to perform traditional aminocarbonylation reactions under exceptionally mild conditions (ambient temperature and pressure), and with a range of weakly nucleophilic substrates.
Atmospheric pressure aminocarbonylation of aryl iodides using palladium nanoparticles supported on MOF-5
Dang, Tuan T.,Zhu, Yinghuai,Ghosh, Subhash C.,Chen, Anqi,Chai, Christina L. L.,Seayad, Abdul M.
supporting information; experimental part, p. 1805 - 1807 (2012/03/08)
An efficient amide synthesis by atmospheric pressure aminocarbonylation using palladium nanoparticles supported on MOF-5 is reported. Interestingly, only 0.5 wt% palladium loading was required to achieve high yields. The catalyst is recyclable and offers negligible palladium leaching.
A novel one-pot synthesis of N-acylindoles from primary aromatic amides
Abid, Mohammed,De Paolis, Omar,T?r?k, Béla
, p. 410 - 412 (2008/09/17)
A novel one-pot synthesis of N-acylindoles via tandem cycloalkylation- annelation is described. This approach is based on the use of a strong solid-acid catalyst, montmorillonite K-10, and microwave irradiation under solvent-free conditions. The tandem cy
A catalytic antibody programmed for torsional activation of amide bond hydrolysis
Aggarwal, Ranjana,Benedetti, Fabio,Berti, Federico,Buchini, Sabrina,Colombatti, Alfonso,Dinon, Francesca,Galasso, Vinicio,Norbedo, Stefano
, p. 3132 - 3142 (2007/10/03)
Amidase antibody 312d6, obtained against the sulfonamide hapten 4a that mimics the transition state for hydrolysis of a distorted amide, accelerates the hydrolysis of the corresponding amides 1a-3a by a factor of 103 at pH 8. The mechanisms of
Reactions entre l'indole et les chlorures d'acides, en milieu basique: Synthese d'amides de l'ortho -2 ethyl, aniline
Bourgeois, Paul,Mesdouze, Jean,Philogene, Emile
, p. 1043 - 1046 (2007/10/02)
Acid chlorides react with indole in alkaline aqueous medium and yield amides of o-aniline which is in fact a trimer of indole.Their formation can be understood as follows: autocondensation of indole to give 2,3-diindole; acylatio
