699-89-8

Basic information

• Product Name: 4,7-DICHLORO-THIENO[2,3-D]PYRIDAZINE
• Synonyms: 4,7-DICHLORO-THIENO[2,3-D]PYRIDAZINE;Thieno[2,3-d]pyridazine, 4,7-dichloro-
• CAS NO: 699-89-8
• Molecular Formula: C₆H₂Cl₂N₂S
• Molecular Weight: 205.07
• Mol File: 699-89-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 157-158 °C
• Boiling Point: 409.605°C at 760 mmHg
• Flash Point: 201.522°C
• Appearance: /
• Density: 1.662g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.715
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: -2?+-.0.40(Predicted)
• CAS DataBase Reference: 4,7-DICHLORO-THIENO[2,3-D]PYRIDAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,7-DICHLORO-THIENO[2,3-D]PYRIDAZINE(699-89-8)
• EPA Substance Registry System: 4,7-DICHLORO-THIENO[2,3-D]PYRIDAZINE(699-89-8)

Safety Data

• Hazardous Substances Data: 699-89-8(Hazardous Substances Data)

Usage

General Description

4,7-Dichloro-thieno[2,3-d]pyridazine is a chemical compound with the molecular formula C5H2Cl2N2S. It is a heterocyclic compound that contains a thieno ring fused to a pyridazine ring, with chlorine substituents at the 4 and 7 positions of the thieno ring. 4,7-DICHLORO-THIENO[2,3-D]PYRIDAZINE has been used in pharmaceutical research and has shown potential as a drug candidate for the treatment of various diseases. It is also used as a building block in organic synthesis to create other chemical compounds. Additionally, 4,7-Dichloro-thieno[2,3-d]pyridazine is known for its ability to form coordination complexes with metal ions, making it useful in materials science and catalysis.

InChI:InChI=1/C6H2Cl2N2S/c7-5-3-1-2-11-4(3)6(8)10-9-5/h1-2H

Upstream product

• 91533-14-1 thieno[2,3-d]pyridazin-4,7-dione 
• 527-72-0 2-thiophenylcarboxylic acid 
• 91533-21-0 5,6-dihydro-thieno[2,3-d]pyridazine-4,7-dione 
• 1451-95-2 thiophene-2,3-dicarboxylic acid 
• 14300-68-6 2,3-Thiophendicarbonsaeure-dimethylester 

Downstream Products

• 19137-21-4 (7-chloro-thieno[2,3-d]pyridazin-4-yl)-phenyl-amine 
• 332013-39-5 7-chloro-4-(4-chlorophenylamino)thieno[2,3-d]pyridazine 
• 332012-36-9 4-[({4-[(4-chlorophenyl)amino]-thieno[2,3-d]pyridazin-7-yl}oxy)methyl]-2-pyridinecarboxamide 
• 332012-43-8 N-(1,3-benzothiazol-6-yl)-N-{4-[(4-chlorophenyl)amino]-thieno[2,3-d]pyridazin-7-yl}amine 

Relevant articles and documents

SUBSTITUTED PYRIDINES AND PYRIDAZINES WITH ANGIOGENESIS INHIBITING ACTIVITY

Substituted pyridines and pyridazines having angiogenesis inhibiting activity and generalized structural formula (I) wherein the ring containing A, B, D, E, and L is phenyl or a nitrogen-containing heterocycle; groups X and Y may be any of a variety of defined linking units; R and R may be defined independent substituents or together may be a ring-defining bridge; ring J may be an aryl, pyridyl, or cycloalkyl group; and G groups may be any of a variety of defined substituents. Pharmaceutical compositions containing these materials, and methods of treating a mammal having a condition characterized by abnormal angiogenesis or hyperpermeability processes using these materials are also disclosed.

Substituted pyridines and pyridazines with angiogenesis inhibiting activity

Substituted pyridazines having angiogenesis inhibiting activity and the generalized structural formula wherein the ring containing A, B, D, E, and L is phenyl or a nitrogen-containing heterocycle; groups X and Y may be any of a variety of defined linking units; R1and R2may be defined independent substituents or together may be a ring-defining bridge; ring J may be an aryl, pyridyl, or cycloalkyl group; and G groups may be any of a variety of defined substituents. Pharmaceutical compositions containing these materials, and methods of treating a mammal having a condition characterized by abnormal angiogenesis or hyperpermiability processes using these materials are also disclosed.