699005-67-9Relevant academic research and scientific papers
A new family of small molecules to probe the reactivation of mutant p53
Myers, Michael C.,Wang, JinLing,Iera, Jaclyn A.,Bang, Jeong-Kyu,Saito, Shin'ichi,Hara, Toshiaki,Zambetti, Gerard P.,Appella, Daniel H.
, p. 6152 - 6153 (2007/10/03)
Cells that express mutant p53 derived from cancers are selectively killed by a new class of small organic molecules. The protein p53 is recognized as one of the most important guardians in the body that prevents tumor development. Mutant forms of p53 are
COMPOUNDS AND RELATED METHODS FOR MUTANT p53 REACTIVATION
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Page/Page column 24; 25, (2008/06/13)
Ketoamine compounds and related methods for reactivation of tumor suppressor protein p53.
Diversity-oriented synthesis of enantiopure N-protected β,β-dialkylserines
Dettwiler, James E.,Lubell, William D.
, p. 318 - 324 (2007/10/03)
A series of enantiomerically pure N-Boc-protected β,β- dialkylserines was synthesized by addition of the appropriate Grignard reagent to N-(Boc)serine methyl ester, followed by TEMPO-catalysed oxidation of the primary alcohol with sodium chlorite and sodi
