699009-95-5Relevant academic research and scientific papers
Oxidative cyclization of diols derived from 1,5-dienes: Formation of enantiopure cis-tetrahydrofurans by using catalytic osmium tetroxide; formal synthesis of (+)-cis-solamin
Donohoe, Timothy J.,Butterworth, Sam
, p. 4766 - 4768 (2007/10/03)
(Chemical Equation Presented) High yields and high levels of stereocontrol are observed in the oxidative cyclization of vicinal diols using catalytic amounts of a transition metal (see scheme; TFA = trifluoroacetic acid). The product stereochemistry is co
Total Synthesis and Preliminary Biological Evaluation of cis-Solamin Isomers
Cecil, Alex R. L.,Hu, Yulai,Vicent, Maria J.,Duncan, Ruth,Brown, Richard C. D.
, p. 3368 - 3374 (2007/10/03)
An efficient total synthesis of cis-solamin (1) has been achieved in 21% overall yield and with a longest linear sequence of just 11 steps from aldehyde 8. A key feature of the approach was the use of asymmetric permanganate-promoted oxidative cyclization
