699010-80-5

Upstream product

• 42134-54-3 3-cyclohexyl-2-propyn-1-ol 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 699011-02-4 (3-methoxymethoxy-1-methyl-propa-1,2-dienyl)-cyclohexane 
• 699010-88-3 tert-butyl-(3-cyclohexyl-1-methoxymethoxy-buta-1,2-dienyl)-dimethyl-silane 
• 1239606-85-9 1-(tert-butyldimethylsilyl)-3-cyclohexylprop-2-yn-1-one 
• 1342799-30-7 1-(tert-butyldimethylsilyl)-3-cyclohexylprop-2-ynyl propionate 

Relevant academic research and scientific papers

Synthesis of optically active α-(allenyl)-and a-substituted-α- (allenyl)glycines

The synthesis of various types of optically active α-(allenylsilane- containing)glycines via a chiralitytransferring ester-enolate Claisen rearrangement of α-acyloxy-a-alkynylsilanes is described. The conversion of the rearranged products into the optically active silicon-free α-(allenyl)-and α-substituted-α-(allenyl)glycines was achieved by the removal of the Me2PhSi-or TMS group from the allene terminus.

Tetrasubstituted allene ethers; synthesis and use in Nazarov reactions

A method for the synthesis of tetrasubstituted allene ethers is described, making use of a reverse Brook rearrangement in the key step. The allene products have been used in the Nazarov cyclization reaction.