699020-10-5

Basic information

• Product Name: dimethyl (2S)-2-{(phenylmethoxy)-N-[benzyloxycarbonyl]carbonylamino}-butane-1,4-dioate
• Synonyms: dimethyl (2S)-2-{(phenylmethoxy)-N-[benzyloxycarbonyl]carbonylamino}-butane-1,4-dioate
• CAS NO: 699020-10-5
• Molecular Weight: 429.427
• Mol File: 699020-10-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: dimethyl (2S)-2-{(phenylmethoxy)-N-[benzyloxycarbonyl]carbonylamino}-butane-1,4-dioate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl (2S)-2-{(phenylmethoxy)-N-[benzyloxycarbonyl]carbonylamino}-butane-1,4-dioate(699020-10-5)
• EPA Substance Registry System: dimethyl (2S)-2-{(phenylmethoxy)-N-[benzyloxycarbonyl]carbonylamino}-butane-1,4-dioate(699020-10-5)

Safety Data

• Hazardous Substances Data: 699020-10-5(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 31139-36-3 dibenzyl dicarbonate 
• 35909-93-4 dimethyl (2S)-2-[(phenylmethoxy)carbonylamino]-butane-1,4-dioate 

Downstream Products

• 35909-93-4 dimethyl (2S)-2-[(phenylmethoxy)carbonylamino]-butane-1,4-dioate 
• 6384-18-5 L-Aspartic acid dimethyl ester 

Relevant articles and documents

First Practical Protection of α-Amino Acids as N, N-Benzyloxycarbamoyl Derivatives

The consecutive treatment of N-Cbz amino protected compounds with LiHMDS and CbzCl provides a practical method for the preparation of N,N-benzyloxycarbamoyl (N,N-di-Cbz) derivatives in good yield. When α-amino acids are used the protection occurs without racemization. The method is compatible with a wide range of other functional and protecting groups. The procedure is also valid for the synthesis of mixed N,N-carbamoyl derivatives.