69909-96-2Relevant academic research and scientific papers
2,3-Diaryl-5-anilino[1,2,4]thiadiazoles as melanocortin MC4 receptor agonists and their effects on feeding behavior in rats
Pan, Kevin,Scott, Malcolm K.,Lee, Daniel H. S.,Fitzpatrick, Louis J.,Crooke, Jeffery J.,Rivero, Ralph A.,Rosenthal, Daniel I.,Vaidya, Anil H.,Zhao, Boyu,Reitz, Allen B.
, p. 185 - 192 (2007/10/03)
The melanocortin-4 receptor (MC4) modulates physiological functions such as feeding behavior, nerve regeneration, and drug addiction. Using a high throughput screen based on 125I-NDP-MSH binding to the human MC4 receptor, we discovered 2,3-diar
Synthesis and regioselective [4+2] cycloaddition/nucleophilic reactions of N-arylamino-1:3-diaza-1:3-butadienes with ketenes and accompanying rearrangements
Dey, Paramita D.,Sharma, Arun K.,Rai, Sachchida N.,Mahajan, Mohinder P.
, p. 7459 - 7468 (2007/10/02)
N-Arylamino-1:3-diaza-1:3-butadienes 4 are shown to undergo regioselective reactions with phenyl- and chloroketenes resulting in high yields of 3-aryl-2-methylthio6-phenyl-4(3H)-pyrimidinones 7. Similar reactions with bromo- and iodoketenes, resulted, via
Reactions of Phenylbenzamidines with Isocyanates and Isothiocyanates
Nair, M. D.,Desai, J. A.
, p. 20 - 23 (2007/10/02)
The reaction of N-aryl benzamidines with phenyl isocyanate (phenyl isothiocyanate) yields the normal adducts, quinazoline-4-ones (4-thiones) or diphenyl ureas (thioureas) depending on the substituent on the aryl group and the reaction conditions.The mechanisms of the various transformations are discussed.
