69965-44-2

Basic information

• Product Name: 1-[2-methyl-3-[4-(phenylthio)phenyl]propyl]-1H-imidazolium chloride
• Synonyms: 1-[2-methyl-3-[4-(phenylthio)phenyl]propyl]-1H-imidazolium chloride
• CAS NO: 69965-44-2
• Molecular Formula: C₁₉H₂₀N₂S*ClH
• Molecular Weight: 344.90144
• EINECS: 274-237-5
• Mol File: 69965-44-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-[2-methyl-3-[4-(phenylthio)phenyl]propyl]-1H-imidazolium chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2-methyl-3-[4-(phenylthio)phenyl]propyl]-1H-imidazolium chloride(69965-44-2)
• EPA Substance Registry System: 1-[2-methyl-3-[4-(phenylthio)phenyl]propyl]-1H-imidazolium chloride(69965-44-2)

Safety Data

• Hazardous Substances Data: 69965-44-2(Hazardous Substances Data)

Usage

Type of Compound

Quaternary ammonium compound

Structure

Long, hydrophobic tail and positively charged imidazolium ring

Classification

Cationic surfactant

Enzyme Inhibition

Highly potent and selective inhibitor of cholesterol esterase (CEase)

Cholesterol Reduction

Effective in reducing cholesterol levels in in vitro and in vivo studies

Potential Applications

Treatment of hypercholesterolemia and related cardiovascular diseases

Anticancer Properties

Shown promising results in inhibiting the growth of tumor cells

Further Research

Needed to understand the mechanism of action and assess potential for clinical use

InChI:InChI=1/C19H20N2S.ClH/c1-16(14-21-12-11-20-15-21)13-17-7-9-19(10-8-17)22-18-5-3-2-4-6-18;/h2-12,15-16H,13-14H2,1H3;1H

Relevant articles and documents

Basic thioethers

Basic thioethers of the formula wherein R is p-R5 -S-phenyl or 2-dibenzothienyl; A is --CHR3 --CHR4 --, --CR3 (OH)--CHR4 --, --CHR3 --CR4 (OH)-- or --CR3 =CR4 --; Z is --NR1 R2, 1-imidazolyl or 1,2,4-triazol-1-yl; n is 1, 2 or 3; R1 and R2 are the same or different and each is H, alkyl of 1-4 carbon atoms or together form alkylene of 4-7 ring carbon atoms, or form 3-oxapentamethylene; R3 and R4 are the same or different and each is H, alkyl of 1-4 carbon atoms or phenyl; R5 is an unsubstituted phenyl or benzyl group or a phenyl or benzyl group substituted with 1 or 2 of halogen, nitro, amino and/or alkoxy of 1-4 carbon atoms, alkyl of 1-6 carbon atoms, or cycloalkyl of 3-7 ring carbon atoms, with the proviso that R5 is alkyl of 1-6 carbon atoms, or cycloalkyl of 3-7 ring carbon atoms when A is --CHR3 --CH2 -- and Z is 1-imidazolyl possess valuable pharmacological properties.