69979-46-0

Upstream product

• 75-52-5 nitromethane 
• 149454-98-8 [(1R,2R,3R,4R)-4-(6-Amino-purin-9-yl)-2,3-bis-benzyloxy-cyclopentyl]-methanol 
• 69979-45-9 6-chloro-9-<(1R,2R,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl>purine 
• 123880-26-2 Acetic acid (1R,2R,3R,5R)-2-acetoxy-5-acetoxymethyl-3-acetylamino-cyclopentyl ester 
• 123880-27-3 5-amino-4-chloro-6-<(1R,2R,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl>aminopyrimidine 
• 856328-53-5 N-((1R,2R,3R,4R)-2,3-Dihydroxy-4-hydroxymethyl-cyclopentyl)-acetamide 
• 123880-25-1 (1R,2R,3R,5R)-3-amino-5-(hydroxymethyl)cyclopentane-1,2-diol 
• 115435-01-3 (3S,4S)-3-(benzyloxy)-1-<<(t-butyldiphenylsilyl)oxy>methyl>-4-hydroxy-1-cyclopentene 
• 123827-58-7 (3S,4R)-4-azido-3-(benzyloxy)-1-cyclopentene-1-methanol 
• 121417-02-5 Benzoic acid (1R,2S,3R,4R,5R)-3-(6-benzoylamino-purin-9-yl)-4-benzyloxy-5-hydroxy-2-nitro-cyclopentylmethyl ester 
• 121417-01-4 Benzoic acid (1R,2S,3R,4R,5R)-3-(6-benzoylamino-purin-9-yl)-4-benzyloxy-5-formyloxy-2-nitro-cyclopentylmethyl ester 
• 121417-03-6 Benzoic acid (1R,2R,3R,4R)-4-(6-benzoylamino-purin-9-yl)-3-benzyloxy-2-(2-ethoxy-ethoxy)-cyclopentylmethyl ester 
• 121417-04-7 Acetic acid (1R,2R,3S,4R,5R)-2-acetoxymethyl-4-(6-benzoylamino-purin-9-yl)-5-benzyloxy-3-nitro-cyclopentyl ester 
• 119826-17-4 Benzoic acid (1R,2R,3R)-3-benzyloxy-2-formyloxy-4-hydroxy-5-nitro-cyclopentylmethyl ester 

Relevant academic research and scientific papers

A highly efficient synthesis of the antiviral agent (+)-cyclaradine involving the regioselective cleavage of epoxide by neighboring participation

(+)-Cyclaradine, carbocyclic arabinofuranosyladenine having anti-HSV activity, has been synthesized from (-)-2-azabicyclo[2.2.1]hept-5-en-3-one in only seven steps. The method involves the novel ring cleavage of epoxide by neighboring participation.

Facile syntheses of pseudo-α-D-arabinofuranose, and two pseudo-D-arabinofuranosylnucleosides, (+)-cyclaradine and (+)-1-pseudo-β-D-arabinofuranosyluracil, from D-arabinose

An optically active pseudo-sugar, pseudo-α-D-arabinofuranose, was efficiently synthesized from D-arabinose by using a stereoselective nitromethane addition reaction to form a branched nitropyranose (6) as a key step. Furthermore, two biologically active p

A new approach to the synthesis of optically active pseudo-sugar and pseudo-nucleoside - Syntheses of pseudo-α-D-arabinofuranose, (+)-cyclaradine, and (+)-1-pseudo-β-D-arabinofuranosyluracil from D-arabinose

An optically active pseudo-sugar, pseudo-α-D-arabinofuranose, was synthesized from D-arabinose in favorable overall yield by using a stereoselective formation of branched nitropyranose as the key step. Furthermore, two biologically active pseudo-β-D-arabi

Adenosine deaminase resistant antiviral purine nucleosides and method of preparation

The preparation of (±)-9-[α-(2α,3β-dihydroxy-4α-(hydroxymethyl) cyclopentyl)]-6-substituted purines: STR1 and (±)-3-[α-(2α, 3β-dihydroxy-4α-(hydroxymethyl)cyclopentyl)]-7-substituted-v-triazolo[4,5d]pyrimidines: STR2 and their derivatives wherein R is amino, mercapto, methylmercapto, hydroxy, halogen, or substituted amino: STR3 wherein R' and R" may be the same or different and are of hydrogen, methyl, ethyl, propyl or phenyl. The preparation of the single intermediate from which either of these series of compounds may be synthesized is also disclosed. The compounds exhibit antiviral and antitumor activity.