700-15-2Relevant academic research and scientific papers
Process for producing 3,5-difluoraniline
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, (2008/06/13)
A process for producing 3,5-difluoroaniline, which comprises reacting a benzonitrile compound of the formula (I): STR1 wherein each of X1, X2 and X3 is hydrogen, chlorine, bromine or a cyano group, provided that at least one of X1 to X3 is a cyano group, with a mineral acid for hydrolysis and decarboxylation to obtain an aniline compound of the formula (II): STR2 wherein each of X4, X5 and X6 is hydrogen, chlorine or bromine, provided that at least one of X4 to X6 is hydrogen, and in the case of a compound of the formula (II) wherein X4, X5 and X6 are not simultaneously hydrogen, reacting such a compound with hydrogen in a presence of a catalyst for reduction to obtain 3,5 -difluoroaniline.
