70000-59-8Relevant articles and documents
Potent and selective CC-chemokine receptor-2 (CCR2) antagonists as a potential treatment for asthma
Lagu, Bharat,Gerchak, Chrissy,Pan, Meng,Hou, Cuifen,Singer, Monica,Malaviya, Ravi,Matheis, Michele,Olini, Gil,Cavender, Druie,Wachter, Michael
, p. 4382 - 4386 (2008/02/09)
A number of compounds bearing a quaternary ammonium moiety were found to be antagonists with nanomolar binding affinity for the chemokine receptor-2. The structure-activity relationships in the series are described herein along with some detailed characte