70028-80-7Relevant academic research and scientific papers
Synthesis of ribosyl-ribosyl-adenosine-5′,5′′,5′′′(triphosphate) - The naturally occurring branched fragment of poly(ADP ribose)
Liu, Qiang,Kistemaker, Hans. A. V.,Overkleeft, Herman S.,Van Der Marel, Gijsbert A.,Filippov, Dmitri V.
, p. 10255 - 10258 (2017)
Poly-adenosine diphosphate ribose (PAR) is a branched biopolymer that occurs as a result of post-translational modification of proteins. In 1981 Miwa et al. determined the structure of enzymatically prepared branched PAR. We present the first synthesis of the same branched PAR fragment and have shown by NMR that the structure proposed by Miwa is correct.
