700348-66-9Relevant academic research and scientific papers
5,5-Dimethyl-2-phenylamino-2-oxazoline as an effective chiral auxiliary for asymmetric alkylations
Le, Thanh Nguyen,Nguyen, Quynh Pham Bao,Kim, Jae Nyoung,Kim, Taek Hyeon
, p. 7834 - 7837 (2008/03/11)
The novel chiral auxiliaries, 5,5-diphenyl-2-phenylamino-2-oxazoline and 5,5-dimethyl-2-phenylamino-2-oxazoline, were prepared from l-valine methyl ester. The 5,5-dimethyl compound was shown to be a particularly effective chiral auxiliary for asymmetric alkylation affording high yields and diastereoselectivities.
