7005-53-0

Basic information

• Product Name: 10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-amine
• Synonyms: 10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-amine;5-Amino-10,11-dihydro-5H-dibenzo[a,d]cycloheptene;10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-amine
• CAS NO: 7005-53-0
• Molecular Formula: C₁₅H₁₅N
• Molecular Weight: 209.2863
• EINECS: 230-280-1
• Mol File: 7005-53-0.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 328.3°C at 760 mmHg
• Flash Point: 159.4°C
• Appearance: /
• Density: 1.093g/cm³
• Vapor Pressure: 0.000191mmHg at 25°C
• Refractive Index: 1.612
• CAS DataBase Reference: 10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-amine(7005-53-0)
• EPA Substance Registry System: 10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-amine(7005-53-0)

Safety Data

• Hazardous Substances Data: 7005-53-0(Hazardous Substances Data)

Usage

General Description

10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-amine, also known as amitriptyline, is a tricyclic antidepressant (TCA) that is used to treat various mental/mood disorders such as depression and anxiety. It functions by affecting the balance of certain natural chemicals (neurotransmitters such as serotonin) in the brain. In addition to mental health usage, it can also be used to treat certain types of nerve pain and to prevent migraines. Amitriptyline, a prescription drug, was originally approved by the FDA in 1961.Despite its effectiveness, usage is limited due to significant side effects and has the potential to be toxic in overdose.

InChI:InChI=1/C15H15N/c16-15-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)15/h1-8,15H,9-10,16H2

Upstream product

• 1785-74-6 10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-one oxime 
• 4985-15-3 Noxiptiline hydrochloride 
• 59631-14-0 N-(10,11-dihydro-5H-dibenzocyclohepten-5-yl)phthalimide 
• 1210-35-1 10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-one 
• 76858-21-4 dibenzocyclohepten-5-imine 
• 2222-33-5 dibenzosuberenon 
• 1210-33-9 5-chlorodibenzosuberane 

Downstream Products

• 145253-62-9 2-(2,3-6,7-dibenzocycloheptanylamino)acetamide 
• 47132-60-5 N-dibenzosuberyl-N',N'-dimethyl-1,2-diaminoethane 
• 103378-87-6 N-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-4-[4-(4-fluoro-phenyl)-piperazin-1-yl]-butyramide 
• 62371-00-0 N-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)formamide 
• 87126-90-7 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylcarbamoyl)-7-oxa-bicyclo[2.2.1]heptane-2-carboxylic acid 
• 151726-50-0 (10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-{2-[(S)-6-(dimethyl-phenyl-silanyl)-cyclohex-1-enyl]-ethyl}-amine 
• 151726-40-8 (10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-{2-[(R)-6-(dimethyl-phenyl-silanyl)-cyclohex-1-enyl]-ethyl}-amine 
• 152510-74-2 (10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-{2-[6-(dimethyl-phenyl-silanyl)-cyclohex-1-enyl]-ethyl}-amine 
• 152510-73-1 (10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-[2-(6-trimethylsilanyl-cyclohex-1-enyl)-ethyl]-amine 
• 310883-05-7 C₂₂H₁₉N 
• 1423077-75-1 4-trifluoromethoxy-N-(2-((10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)amino)ethyl)benzenesulfonamide 
• 1423077-74-0 4-chloro-N-(2-((10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)amino)ethyl)benzenesulfonamide 

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