700805-72-7

Basic information

• Product Name: Carbamimidic acid, N-[4-(aminosulfonyl)phenyl]-N'-cyano-, phenyl ester
• CAS NO: 700805-72-7
• Molecular Formula: C14H12N4O3S
• Molecular Weight: 316.34
• Mol File: 700805-72-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Carbamimidic acid, N-[4-(aminosulfonyl)phenyl]-N'-cyano-, phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamimidic acid, N-[4-(aminosulfonyl)phenyl]-N'-cyano-, phenyl ester(700805-72-7)
• EPA Substance Registry System: Carbamimidic acid, N-[4-(aminosulfonyl)phenyl]-N'-cyano-, phenyl ester(700805-72-7)

Safety Data

• Hazardous Substances Data: 700805-72-7(Hazardous Substances Data)

Upstream product

• 79463-77-7 N-cyanodiphenylcarbonimidate 
• 63-74-1 sulfanilamide 

Downstream Products

• 863030-68-6 N₃-[(4-aminosulfonyl)phenyl]-1-(4'-nitrobenzoyl)-1H-1,2,4-triazole-3,5-diamine 
• 886584-09-4 3-(S)-{6-[5-amino-3-(4-sulfamoylphenylamino)-[1,2,4]triazol-1-yl]-5-methoxypyrimidin-4-ylamino}piperidine-1-carboxylic acid tert-butyl ester 
• 844890-58-0 4-[5-amino-1-(2-chloro-pyridin-4-yl)-1H-[1,2,4]triazol-3-ylamino]-benzenesulfonamide 
• 863030-75-5 N₃-[(4-aminosulfonyl)phenyl]-1-(4'-chlorobenzoyl)-1H-1,2,4-triazole-3,5-diamine 
• 863030-71-1 N₃-[(4-aminosulfonyl)phenyl]-1-(4'-methoxybenzoyl)-1H-1,2,4-triazole-3,5-diamine 
• 443797-96-4 4-[[5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-yl]amino]benzenesulfonamide 
• 443798-17-2 N₃-[(4-aminosulfonyl)phenyl]-1-(2'-furanoyl)-1H-1,2,4-triazole-3,5-diamine 
• 863030-73-3 N₃-[(4-aminosulfonyl)phenyl]-1-(acetyl)-1H-1,2,4-triazole-3,5-diamine 
• 443799-31-3 4-((5-amino-1H-1,2,4-triazol-3-yl)amino)benzenesulfonamide 
• 863030-65-3 N₃-[(4-aminosulfonyl)phenyl]-1-[3'-(trifluoromethyl)benzoyl]-1H-1,2,4-triazole-3,5-diamine 
• 863030-66-4 N₃-[(4-aminosulfonyl)phenyl]-1-(3'-bromobenzoyl)-1H-1,2,4-triazole-3,5-diamine 
• 863030-62-0 N₃-[(4-aminosulfonyl)phenyl]-1-(2'-methoxybenzoyl)-1H-1,2,4-triazole-3,5-diamine 
• 863030-64-2 N₃-[(4-aminosulfonyl)phenyl]-1-(3'-nitrobenzoyl)-1H-1,2,4-triazole-3,5-diamine 
• 863030-70-0 N₃-[(4-aminosulfonyl)phenyl]-1-(4'-phenylbenzoyl)-1H-1,2,4-triazole-3,5-diamine 

Relevant articles and documents

Selective Janus Kinase 2 (JAK2) Pseudokinase Ligands with a Diaminotriazole Core

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DIAMINOTRIAZOLE COMPOUNDS USEFUL AS INHIBITORS OF PROTEIN KINASES

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1-Acyl-1H-[1,2,4]triazole-3,5-diamine analogues as novel and potent anticancer cyclin-dependent kinase inhibitors: Synthesis and evaluation of biological activities

A series of 1-acyl-1H-[1,2,4]triazole-3,5-diamine analogues were synthesized as cyclin-dependent kinase (CDK) inhibitors. These compounds showed potent and selective CDK1 and CDK2 inhibitory activities and inhibited in vitro cellular proliferation in various human tumor cells. Representative compound 3b demonstrated in vivo efficacy in a human melanoma A375 xenograft model in nude mice.