7012-92-2Relevant academic research and scientific papers
One pot synthesis of some new N-allyl and N-benzyl quinazolinones and their anti-inflammatory activity
Sudula, Sudharshan Reddy,Jala, Ranjith,Siddoju, Kavitha,Ega, Jagadeesh Kumar
, (2021/06/28)
The simple and more reliable one-pot synthesis of some novel compounds of allyl/Benzyl quinazolinone (4aa-4bd) with good yields from readily available derivatives of anthranilic acid and benzoyl chloride was also reported. Interestingly, as compared to Di
Tandem Oxidative Cyclocondensation towards 2,3-Disubstituted Quinazolinones in the Presence of [Bmim][BF4] and Iodine
Sofi, Firdoos Ahmad,Sharma, Rohit,Chakraborti, Asit K.,Bharatam, Prasad V.
supporting information, p. 5887 - 5893 (2019/08/12)
The metal-free synthesis of 2-aryl-3-arylmethylquinazolin-4(3H)-one is achieved through ionic liquid mediated and I2-promoted tandem oxidative cyclocondensation of isatoic anhydrides with arylmethylamines as the common precursor for the 2-aryl
Rhodium(II)-Catalyzed Carbenoid Insertion of N-Tosylhydrazones into Amide N-H Bonds: An Efficient Approach to N3-Benzyl/Alkyl-2-arylquinazolinones
Lingayya, Rajaka,Vellakkaran, Mari,Nagaiah, Kommu,Nanubolu, Jagadeesh Babu
, p. 81 - 89 (2016/01/25)
Dirhodium(II) acetate-catalyzed reactions of N-tosylhydrazones with dihydroquinazolinones bearing different types of N-H bonds that give N3-benzyl/alkyl-2-arylquinazolin-4(3H)-ones through Csp3-N bond formation by oxidative dehydroge
Ligand-Free Pd-Catalyzed and Copper-Assisted C-H Arylation of Quinazolin-4-ones with Aryl Iodides under Microwave Heating
Laclef, Sylvain,Harari, Marine,Godeau, Julien,Schmitz-Afonso, Isabelle,Bischoff, Laurent,Hoarau, Christophe,Levacher, Vincent,Fruit, Corinne,Besson, Thierry
, p. 1700 - 1703 (2015/04/14)
A microwave-assisted method for the palladium-catalyzed direct arylation of quinazolin-4-one has been developed under copper-assistance. This method is applicable to a wide range of aryl iodides and substituted (2H)-quinazolin-4-ones. This protocol provides a simple and efficient way to synthesize biologically relevant 2-arylquinazolin-4-one backbones.
Copper-catalyzed redox-neutral C-H amination with amidoximes
Chen, Hui,Chiba, Shunsuke
supporting information, p. 42 - 46 (2014/01/06)
CuI-catalyzed reactions of N-alkylamidoximes afforded dihydroimidazoles via sp3 C-H amination. On the other hand, the reactions of N-benzoylamidoximes resulted in sp2 C-H amination to form quinazolinones. The reaction mechanisms could be characterized as a redox-neutral radical pathway including a Cu(i)-Cu(ii) redox catalytic cycle. The Royal Society of Chemistry.
