Welcome to LookChem.com Sign In|Join Free

CAS

  • or

701213-08-3

1-(4-benzoylpiperazin-1-yl)-2-(4-methoxy-7-(3-((methylamino)methyl)-1H-pyrazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

701213-08-3 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

  • 1-(4-benzoylpiperazin-1-yl)-2-(4-methoxy-7-(3-((methylamino)methyl)-1H-pyrazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione

    Cas No: 701213-08-3

  • Need to discuss

  • No requirement

  • Adequate

  • Ality Chemical Corporation
  • Contact Supplier
  • 701213-08-3 Structure

  • Basic information

    1. Product Name: 1-(4-benzoylpiperazin-1-yl)-2-(4-methoxy-7-(3-((methylamino)methyl)-1H-pyrazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione
    2. Synonyms: 1-(4-benzoylpiperazin-1-yl)-2-(4-methoxy-7-(3-((methylamino)methyl)-1H-pyrazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione
    3. CAS NO:701213-08-3
    4. Molecular Formula:
    5. Molecular Weight: 501.545
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 701213-08-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-(4-benzoylpiperazin-1-yl)-2-(4-methoxy-7-(3-((methylamino)methyl)-1H-pyrazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-(4-benzoylpiperazin-1-yl)-2-(4-methoxy-7-(3-((methylamino)methyl)-1H-pyrazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione(701213-08-3)
    11. EPA Substance Registry System: 1-(4-benzoylpiperazin-1-yl)-2-(4-methoxy-7-(3-((methylamino)methyl)-1H-pyrazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione(701213-08-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 701213-08-3(Hazardous Substances Data)

701213-08-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 701213-08-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,0,1,2,1 and 3 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 701213-08:
(8*7)+(7*0)+(6*1)+(5*2)+(4*1)+(3*3)+(2*0)+(1*8)=93
93 % 10 = 3
So 701213-08-3 is a valid CAS Registry Number.

701213-08-3Downstream Products

701213-08-3Relevant articles and documents

Discovery of the Human Immunodeficiency Virus Type 1 (HIV-1) Attachment Inhibitor Temsavir and Its Phosphonooxymethyl Prodrug Fostemsavir

Wang, Tao,Ueda, Yasu,Zhang, Zhongxing,Yin, Zhiwei,Matiskella, John,Pearce, Bradley C.,Yang, Zheng,Zheng, Ming,Parker, Dawn D.,Yamanaka, Gregory A.,Gong, Yi-Fei,Ho, Hsu-Tso,Colonno, Richard J.,Langley, David R.,Lin, Pin-Fang,Meanwell, Nicholas A.,Kadow, John F.

, p. 6308 - 6327 (2018/06/27)

The optimization of the 4-methoxy-6-azaindole series of HIV-1 attachment inhibitors (AIs) that originated with 1 to deliver temsavir (3, BMS-626529) is described. The most beneficial increases in potency and pharmacokinetic (PK) properties were attained by incorporating N-linked, sp2-hybridized heteroaryl rings at the 7-position of the heterocyclic nucleus. Compounds that adhered to a coplanarity model afforded targeted antiviral potency, leading to the identification of 3 with characteristics that provided for targeted exposure and PK properties in three preclinical species. However, the physical properties of 3 limited plasma exposure at higher doses, both in preclinical studies and in clinical trials as the result of dissolution- and/or solubility-limited absorption, a deficiency addressed by the preparation of the phosphonooxymethyl prodrug 4 (BMS-663068, fostemsavir). An extended-release formulation of 4 is currently in phase III clinical trials where it has shown promise as part of a drug combination therapy in highly treatment-experienced HIV-1 infected patients.

Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives

-

, (2008/06/13)

This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives. These compounds possess unique antiv

Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives

-

Page 198, (2008/06/13)

This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 701213-08-3