701291-89-6

Upstream product

• 536-57-2 p-toluene sulfinic acid 
• 5994-87-6 diphenylphosphinamide 
• 2043-61-0 cyclohexanecarbaldehyde 

Downstream Products

• 1251771-88-6 C₂₅H₂₆NOPS 
• 1251771-85-3 C₂₇H₂₈NOP 
• 881694-07-1 N-cyclohexylmethylenediphenylphosphinamide 
• 1566557-12-7 (R)-N-(1-cyclohexyl-2-(trimethylsilyl)buta-2,3-dien-1-yl)-P,P-diphenylphosphinic amide 
• 881694-10-6 (2S,3S)-3-cyclohexyl-2-hydroxy-1-phenyl-3-(N-diphenylphosphinoylamino)-1-propanone 

Relevant academic research and scientific papers

Design and synthesis of a tridentate ligand inspired by the phenomenon of self-assembly catalysis and its application in the asymmetric alkynylation of N-(diphenylphosphinoyl) imines

On the basis of the phenomenon of self-assembly catalysis, a tridentate ligand was designed and synthesized in two steps. The application in alkynylation of N-(diphenylphosphinoyl) imines gave the expected products. Aromatic, heteroaromatic N-(diphenylphosphinoyl) imines were employed and gave optically active propargylic amines in good yields (up to 89%) and excellent enantioselectivities (up to 96%) by a simple experimental procedure. The direct use of sulfone amides in the alkynylation of N-(diphenylphosphinoyl) aliphatic imines made this method very attractive.

Trichloromethyl ketones as synthetically versatile donors: Application in direct catalytic mannich-type reactions and the stereoselective synthesis of azetidines

Chemical transformers! Catalytic nucleophilic activation of trichloromethyl ketones allows applications in intermolecular carbon-carbon bond-forming reactions. Mannich adducts such as azetidines can be obtained from the primary products in high yield and syn selectivity. PG = protecting group. (Chemical Equation Presented)