701291-95-4Relevant academic research and scientific papers
Trichloromethyl ketones as synthetically versatile donors: Application in direct catalytic mannich-type reactions and the stereoselective synthesis of azetidines
Morimoto, Hiroyuki,Wiedemann, Sean H.,Yamaguchi, Akitake,Harada, Shinji,Chen, Zhihua,Matsunaga, Shigeki,Shibasaki, Masakatsu
, p. 3146 - 3150 (2007/10/03)
Chemical transformers! Catalytic nucleophilic activation of trichloromethyl ketones allows applications in intermolecular carbon-carbon bond-forming reactions. Mannich adducts such as azetidines can be obtained from the primary products in high yield and syn selectivity. PG = protecting group. (Chemical Equation Presented)
