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Z-LYS-PNA, also known as N-benzyloxycarbonyl-L-lysine 2-naphtylamide, is a synthetic peptide derivative commonly used in various biochemical and biophysical studies. It is a chromogenic substrate for proteases, particularly for lysosomal cysteine proteases like cathepsins B, H, and L. The compound is designed to mimic the natural substrates of these enzymes, allowing researchers to study their activity and inhibition. Upon cleavage by the protease, the release of the 2-naphtylamide group results in a color change, which can be quantified to assess enzyme activity. Z-LYS-PNA is also used in high-throughput screening assays to identify potential inhibitors of these proteases, which are implicated in various diseases, including cancer and neurodegenerative disorders. Its synthetic nature and specific substrate properties make Z-LYS-PNA a valuable tool in the field of enzymology and drug discovery.

70144-71-7

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70144-71-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 70144-71-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,1,4 and 4 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 70144-71:
(7*7)+(6*0)+(5*1)+(4*4)+(3*4)+(2*7)+(1*1)=97
97 % 10 = 7
So 70144-71-7 is a valid CAS Registry Number.
InChI:InChI=1/C20H24N4O5/c21-13-5-4-8-18(23-20(26)29-14-15-6-2-1-3-7-15)19(25)22-16-9-11-17(12-10-16)24(27)28/h1-3,6-7,9-12,18H,4-5,8,13-14,21H2,(H,22,25)(H,23,26)/t18-/m0/s1

70144-71-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name Z-LYS-PNA

1.2 Other means of identification

Product number -
Other names Z-L-LYSINE P-NITROANILIDE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:70144-71-7 SDS

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