70170-87-5Relevant academic research and scientific papers
Synthesis of some modified aurones as antileukemic and antibacterial agents
Deepthi,Harinadha, Babu V,Madhava, Reddy B
, p. 1455 - 1461 (2014/01/06)
Cyclisation of 1-(2-hydroxyphenyl)-3-substituted phenylprop-2-en-1-ones 1a-h in pyridine with mercuric acetate gives different 2-benzylidene-1- benzofuran-3(2H)-ones 2a-h which on subsequent reaction with hydroxylamine hydrochloride affords 2-benzylidene-
Amine-effected cyclization of chalcone dihalides to aurones
Donnelly, John A.,Emerson, Geraldine M.
, p. 7227 - 7236 (2007/10/02)
The possibility of employing the amine-catalysed cyclization of αβ-dibromodihydrochalcones and α-bromochalcones as a general synthesis of aurones was studied using cyclohexylamine and the most representative member of each class of these αβ-disubstituted ketones and α-halogeno chalcones. Overall yields of heterocyclic products were generally poor except from 4′6′-dimethoxy- and 3-nitro-substituted chalcone systems; aurones were obtained in fair yield from the former and in excellent yield from the latter. 22′-Diacetoxychalcone dibromide and 22′-diacetoxy-α-bromochalcone cyclised to a 2-benzoylbenzofuran to the exclusion of the corresponding aurone and flavone.
