70170-91-1

Usage

Chemical Properties

off-white to light yellow powder

InChI:InChI=1/C10H10O4/c11-9(12)6-3-7-1-4-8(5-2-7)10(13)14/h1-2,4-5H,3,6H2,(H,11,12)(H,13,14)/p-2

Upstream product

• 123-08-0 4-hydroxy-benzaldehyde 
• 107-94-8 chloropropionic acid 
• 99186-35-3 4-(3-hydroxypropoxy)benzaldehyde 
• 1044161-89-8 4-(3-oxopropoxy)benzaldehyde 

Downstream Products

• 1415995-78-6 ethyl 3-[4-{bis(2-methyl-1H-indol-3-yl)methyl}phenoxy]propionate 
• 1415995-36-6 ethyl 3-[4-{bis(1H-indol-3-yl)methyl}phenoxy]propionate 
• 1621460-57-8 3-{4-[(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl]phenoxy}propanoic acid 
• 1418760-06-1 C₈H₁₀N₄O₂*C₁₀H₁₀O₄ 
• 1099614-15-9 ethyl 3-(4-formylphenoxy)propionate 

Relevant academic research and scientific papers

An efficient one pot syntheses of aryl-3,3′-bis(indolyl)methanes and studies on their spectral characteristics, DPPH radical scavenging-, antimicrobial-, cytotoxicity-, and antituberculosis activity

An efficient one-pot syntheses of aryl-3,3′-bis(indolyl)methanes (BIMs) from indole/2-methylindole and formylphenoxyaliphatic acid(s) is described. Esterification of carboxylic acid and aromatic electrophilic substitution reactions are achieved simultaneous in the presence of potash alum as a catalyst. This catalyst could be recovered and reused without substantial loss in its catalytic activity and the methodology could be applied on a range of closely related substrates. The solvation characteristics in ground and excited states of the compounds by monitoring the absorbance and fluorescence band maxima have been studied. The fluorescence studies in protic and aprotic solvents were rationalized on the basis of solute-solvent interaction and substituents effect on these photophysical processes analyzed. The compounds prepared showed efficient antimicrobial effect against human pathogens, cytotoxicity against A431 cell line, and DPPH radical scavenging effect. Single crystal XRD studies have been carried out for a few compounds synthesized in this work.

Selective oxoammonium salt oxidations of alcohols to aldehydes and aldehydes to carboxylic acids

The oxidation of alcohols to aldehydes using stoichiometric 4-acetamido-2,2,6,6-tetramethylpiperidine-1-oxoammonium tetrafluoroborate (1) in CH2Cl2 at room temperature is a highly selective process favoring reaction at the carbinol center best able to accommodate a positive charge. The oxidation of aldehydes to carboxylic acids by 1 in wet acetonitrile is also selective; the rate of the process correlates with the concentration of aldehyde hydrate. A convenient and high yield method for oxidation of alcohols directly to carboxylic acids has been developed.