70175-71-2

Basic information

• Product Name: 2,6-bis-[(N-phenyl-glycyl)-amino]-benzo[1,2-d;5,4-d']bisthiazole
• CAS NO: 70175-71-2
• Molecular Weight: 488.594
• Mol File: 70175-71-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2,6-bis-[(N-phenyl-glycyl)-amino]-benzo[1,2-d;5,4-d']bisthiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-bis-[(N-phenyl-glycyl)-amino]-benzo[1,2-d;5,4-d']bisthiazole(70175-71-2)
• EPA Substance Registry System: 2,6-bis-[(N-phenyl-glycyl)-amino]-benzo[1,2-d;5,4-d']bisthiazole(70175-71-2)

Safety Data

• Hazardous Substances Data: 70175-71-2(Hazardous Substances Data)

Upstream product

• 2216-92-4 N-phenylglycine ethyl ester 
• 2789-24-4 2,6-diaminobenzo<1,2-d:5,4-d'>bisthiazole 

Relevant articles and documents

Bis Basic Substituted Diaminobenzobisthiazoles as Potential Antiarthritic Agents

A series of benzobisthiazoles were screened for antiinflammatory activity in the carrageenan paw edema and adjuvant arthritis tests.Compound 26, 2,6-bis(N,N-diethylamino)benzobisthiazole, was found to inhibit the swelling of the uninjected paw in the prophylactic adjuvant arthritis model with an ED50 of 2.3 mg/kg orally.As with most compounds of this series, 26 was inactive in acute model of inflammation, such as paw edema: like steroids, it showed activity in the granuloma pouch assay but did not inhibit cyclooxygenase, indicating a mode of action different from the classical nonsteroidal antiinflammatory drugs (NSAID's).At doses higher than those producing antiinflammatory activity, 26 had some immunoregulating properties.