70181-00-9Relevant academic research and scientific papers
Method for enhancing memory or correcting memory deficiency with arylamidopyrazolidines and arylamidodiazabicycloalkanes
-
, (2008/06/13)
A pharmaceutical method for improving memory or correcting memory deficiency is disclosed, utilizing compounds having the formula: STR1 wherein m and n are zero and one and when m is zero, the dotted line represents a double bond; X is oxygen or sulfur; R1 and R2 are hydrogen, loweralkyl, phenyl or phenylloweralkyl, or R1 and R2 taken together may form a fused second ring with the nitrogen atoms having three or four methylene groups to which may be attached at any second ring carbon atom thereof, a loweralkyl or phenyl radical; R3 is hydrogen or loweralkyl; Ar is phenyl, pyridyl, furanyl, thienyl, methoxy-1H-benzotriazolyl, indolinyl, methoxyindolinyl, methoxypyrimidinyl, aminomethoxypyrimidinyl, 1,3-benzodioxolyl or naphthalenyl, the active optical isomers; and the pharmaceutically acceptable acid addition salts thereof.
N-(4-Pyrazolidinyl)benzamides and their amino precursors
-
, (2008/06/13)
N-(4-Pyrazolidinyl)benzamides having the formula STR1 and their amino precursors are disclosed wherein R is lower alkyl, lower cycloalkyl or phenyllower-alkyl; R1 is lower alkyl, lower cycloalkyl, or phenyllower-alkyl; R2 is hydrogen, lower alkyl or phenyl; R3 is hydroxy, cyano, nitro, amino, fluoro, chloro, bromo, trifluoromethyl, lower alkyl, lower alkoxy, sulfamoyl or actamido, R3 can be the same radical or different radicals; n is an integer from zero to three inclusive, and pharmaceutically acceptable acid addition salts thereof. The compounds have anti-emetic and gastric emptying properties.
