Cas 701906-70-9,{5-[2-(4-amino-benzyloxy)-ethyl]-6-oxo-6,11-dihydro-5H-dibenzo[b,e]azepin-11-yl}-acetic acid methyl ester

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Check Digit Verification of cas no

The CAS Registry Mumber 701906-70-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,0,1,9,0 and 6 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 701906-70:
(8*7)+(7*0)+(6*1)+(5*9)+(4*0)+(3*6)+(2*7)+(1*0)=139
139 % 10 = 9
So 701906-70-9 is a valid CAS Registry Number.

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701906-70-9Relevant academic research and scientific papers

Synthesis and SAR of N-substituted dibenzazepinone derivatives as novel potent and selective αVβ3 antagonists

Kling, Andreas,Backfisch, Gisela,Delzer, Juergen,Geneste, Herve,Graef, Claudia,Holzenkamp, Uta,Hornberger, Wilfried,Lange, Udo E.W,Lauterbach, Arnulf,Mack, Helmut,Seitz, Werner,Subkowski, Thomas

, p. 441 - 446 (2007/10/03)

Synthesis and SARs of new integrin αVβ3 antagonists based on an N-substituted dibenzazepinone scaffold are described. Variation of spacer and guanidine mimetic led to potent compounds exhibiting an IC50 towards αVβ3 in the nanomolar range, high selectivity versus integrin αIIbβ3 and efficacy in functional cellular assays.

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