702-50-1

Basic information

• Product Name: 2,2,5,5-Tetramethylcyclohexane-1,3-dione
• Synonyms: 2,2,5,5-Tetramethyl-1,3-cyclohexanedione;2,2,5,5-Tetramethylcyclohexane-1,3-dione;2,2-Dimethyldimedone;Dimethylmethone
• CAS NO: 702-50-1
• Molecular Formula: C₁₀H₁₆O₂
• Molecular Weight: 168.2328
• Mol File: 702-50-1.mol
• Article Data: 9

Chemical Properties

• Melting Point: 95 °C
• Boiling Point: 245.8°Cat760mmHg
• Flash Point: 90.1°C
• Appearance: /
• Density: 0.954g/cm³
• Vapor Pressure: 0.0282mmHg at 25°C
• Refractive Index: 1.441
• Solubility: Chloroform
• CAS DataBase Reference: 2,2,5,5-Tetramethylcyclohexane-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,5,5-Tetramethylcyclohexane-1,3-dione(702-50-1)
• EPA Substance Registry System: 2,2,5,5-Tetramethylcyclohexane-1,3-dione(702-50-1)

Safety Data

• Hazardous Substances Data: 702-50-1(Hazardous Substances Data)

Usage

Uses

2,?2,?5,?5-?Tetramethyl-1,?3-?cyclohexanedione is an intermediate in synthesizing (+)-cis-Phenothrin (P318100), an isomer of Phenothrin (P318095), which is a pesticide used in the control of pests and insects.

InChI:InChI=1/C10H16O2/c1-9(2)5-7(11)10(3,4)8(12)6-9/h5-6H2,1-4H3

Upstream product

• 126-81-8 dimedone 
• 74-88-4 methyl iodide 
• 1703-81-7 6-isopropylidene-4,4-dimethyl-tetrahydro-pyran-2-one 
• 33225-78-4 Sodium; 2,5,5-trimethyl-3-oxo-cyclohex-1-enolate 

Downstream Products

• 1703-82-8 3-hydroxy-2,2,5,5-tetramethylcyclohexanone 
• 3886-71-3 (1R,3S)-2,2,5,5-tetramethylcyclohexane-1,3-diol 
• 3886-71-3 dl 2,2,5,5-tetramethyl-cyclohexane-1,3-diol 
• 13820-21-8 2,2,5,5-Tetramethyl-cyclohexa-4-ol-1,3-dion-acetat 
• 13988-72-2 Acetic acid (1S,3R)-3-acetoxy-2,2,5,5-tetramethyl-4,6-dioxo-cyclohexyl ester 
• 91008-61-6 2,2,5,5-tetramethyl-cyclohexane-1,3-diol 
• 42221-72-7 4-bromo-2,2,5,5-tetramethylcyclohexane-1,3-dione 
• 21081-47-0 2,2,5,5-tetramethylcyclohexanedione 1,3-bis-phenylhydrazone 
• 57441-20-0 3-Hydroxy-2,2,5,5-tetramethyl-3-phenyl-cyclohexanone 
• 57441-21-1 2,2,5,5-Tetramethyl-1,3-diphenyl-cyclohexane-1,3-diol 

Relevant articles and documents

Acylative desymmetrization of cyclic meso-1,3-diols by chiral DMAP derivatives

An efficient enantioselective acylative desymmetrization of cyclic meso-1,3-diols was developed by using a chiral DMAP derivative 1e having a 1,1¤-binaphthyl unit. The reactions required only 0.5mol% of the catalyst and showed good to excellent enantioselectivity. With this transformation, 5a, a key building block for the synthesis of natural products, was easily obtained in almost enantiomerically pure form after a single recrystallization. Control experiments revealed that tert-alcohol units on the catalyst were responsible for both the catalytic activity and enantioselectivity.

SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS AS RXR AGONISTS

The present invention relates to certain substituted bicyclic compounds that are agonists of RXR and which are therefore useful in the treatment of certain disorders that can be prevented or treated by activation of this receptor. In addition the invention relates to the compounds, methods for their preparation, pharmaceutical compositions containing the compounds and the uses of these compounds in the treatment of certain disorders.

Structure Elucidation of Some Product Obtained by Acid-Catalyzed Condensation of Indole with Acetone

Acid-induced condensation reactions between indole and acetone have been invetigated under different reaction conditions.The structures of the 2:2 condensation products have been elucidated and supported by independent syntheses.A new acid-induced annulat