70201-60-4

Basic information

• Product Name: 2'-isopropoxyacetophenone tosylhydrazone
• Synonyms: 2'-isopropoxyacetophenone tosylhydrazone
• CAS NO: 70201-60-4
• Molecular Weight: 346.45
• Mol File: 70201-60-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2'-isopropoxyacetophenone tosylhydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-isopropoxyacetophenone tosylhydrazone(70201-60-4)
• EPA Substance Registry System: 2'-isopropoxyacetophenone tosylhydrazone(70201-60-4)

Safety Data

• Hazardous Substances Data: 70201-60-4(Hazardous Substances Data)

Upstream product

• 118-93-4 o-hydroxyacetophenone 
• 70201-54-6 1-(2-(1-methylethoxy)phenyl)ethanone 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 

Relevant articles and documents

Achieving Site Selectivity in Metal-Catalyzed Electron-Rich Carbene Transfer Reactions from N-Tosylhydrazones

Catalyst control of the site-selectivity of electron-rich alkyl, aryl disubstituted carbenes generated in situ from o-alkenyl-substituted N-tosylhydrazones was achieved in this study. Exposure of these substrates to copper iodide triggered the formation of α-alkoxy 2H-naphthalenones. This investigation established that changing the catalyst to a rhodium(II) carboxylate turned off cyclization and migration of the electron-rich metal carbene with the β-carboxylate and turned on allylic C-H bond functionalization to diastereoselectively afford 1H-indenes. Examination of the scope of this reaction revealed that ethereal, aminomethylene, and unactivated 2° C-H bonds could be functionalized.