70205-04-8

Usage

Uses

Used in Pharmaceutical Industry:
4-[(4-CHLOROBENZYL)OXY]-3-METHOXYBENZENECARBALDEHYDE is used as a key intermediate in the synthesis of various pharmaceutical products. Its unique chemical structure allows it to be a versatile building block for the development of new drugs and medicinal compounds.
Used in Chemical Industry:
In the chemical industry, 4-[(4-CHLOROBENZYL)OXY]-3-METHOXYBENZENECARBALDEHYDE serves as a raw material for the production of specialty chemicals and fine chemicals. Its specific functional groups and structural features make it suitable for various chemical reactions and processes.
Used in Medicinal Research:
4-[(4-CHLOROBENZYL)OXY]-3-METHOXYBENZENECARBALDEHYDE is utilized in medicinal research for the exploration of its potential biological activities and therapeutic effects. Its unique chemical properties may contribute to the discovery of new drug candidates and the advancement of drug development.
Used in Drug Development:
Due to its distinctive chemical structure, 4-[(4-CHLOROBENZYL)OXY]-3-METHOXYBENZENECARBALDEHYDE plays a role in drug development as a potential lead compound. Researchers can modify its structure to optimize its pharmacological properties, leading to the creation of novel and effective drugs for various medical conditions.

InChI:InChI=1/C15H13ClO3/c1-18-15-8-12(9-17)4-7-14(15)19-10-11-2-5-13(16)6-3-11/h2-9H,10H2,1H3

Upstream product

• 121-33-5 vanillin 
• 622-95-7 4-chlorobenzyl bromide 

Downstream Products

• 316159-56-5 C₁₆H₁₆ClN₃O₂S 

Relevant academic research and scientific papers

Design, synthesis, biological evaluation and in silico study of benzyloxybenzaldehyde derivatives as selective aldh1a3 inhibitors

Aldehyde dehydrogenase 1A3 (ALDH1A3) has recently gained attention from researchers in the cancer field. Several studies have reported ALDH1A3 overexpression in different cancer types, which has been found to correlate with poor treatment recovery. Theref

Novel vanillin derivatives containing a 1,3,4-thiadiazole moiety as potential antibacterial agents

In this study, thirty-four novel vanillin derivatives containing a 1,3,4-thiadiazole structure were obtained and their antibacterial activities were evaluated. The results indicate that most of the title compounds displayed inhibitory effects on Xanthomonas oryzae pv. oryzae (Xoo) and Xanthomonas oryzae pv. oryzicola (Xoc). Among them, compound 29 exhibited excellent antibacterial activities against Xoo and Xoc in vitro, with the EC50 values of 3.14 and 8.83 μg/mL, respectively, much superior to thiodiazole copper (87.03 and 108.99 μg/mL) and bismerthiazol (67.64 and 79.26 μg/mL). Under greenhouse condition, the protective efficiency of compound 29 against rice bacterial leaf blight was 49.34%, and curative efficiency was 40.96%. In addition, compound 29 can reduce the exopolysaccharides production of Xoo, increase the permeability of cell membrane and damage cell membrane.

PYRROLO[2,3-B] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS

Compounds of formula III which are active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.

SUBSTITUTED 4-BENZYLOXY-PHENYLMETHYLAMIDE DERIVATIVES AS COLD MENTHOL RECEPTOR-1 (CMR-1) ANTAGONISTS FOR THE TREATMENT OF UROLOGICAL DISORDER

The present invention relates to novel substituted benzyloxy-phenylmethylamide derivatives of formula (I), processes for their preparation, and their use in medicaments, especially for the prophylaxis and treatment of diseases associated with Cold Menthol