Welcome to LookChem.com Sign In|Join Free

CAS

  • or

70219-46-4

Post Buying Request

70219-46-4 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

70219-46-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 70219-46-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,2,1 and 9 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 70219-46:
(7*7)+(6*0)+(5*2)+(4*1)+(3*9)+(2*4)+(1*6)=104
104 % 10 = 4
So 70219-46-4 is a valid CAS Registry Number.

70219-46-4Downstream Products

70219-46-4Relevant articles and documents

Regio- and Stereoselective Cyclopentannulation with Ketones and Propargyl Alcohol Derivatives. Synthesis of dl-Nootkatone and dl-Muscopyridine

Hiyama, Tamejiro,Shinoda, Masaki,Saimoto, Hiroyuki,Nozaki, Hitosi

, p. 2747 - 2758 (2007/10/02)

A highly regio- and stereoselective five-membered ring annulation involving the acid-treatment of propargyl alcohol dianion adducts of ketones is described.The propargyl alcohol adduct of 2-octanone was converted into 2-methyl-3-pentyl-2-cyclopentenone by treatment with sulfuric acid-methanol (1:1) at 0 deg C.As the major product, 1-methylbicyclodec-6-en-8-one was produced from 2-methylcycloheptanone.Remarkable regioselective cyclopentannulation was observed in 2-methylcyclohexanone and 2,3-dimethylcyclohexanone wherein 1-methyl- and trans-1,2-dimethyl-substituted bicyclonon-5-en-7-one (BNO) are produced, respectively.With 3-butyn-2-ol, 2-methylcyclohexanone was converted into the cis-1,9-dimethyl-substituted BNO. 4-Isopropyl-2-methylcyclohexanone was transformed into an 83-85:17-15 mixture of c-3-isopropyl-r-1,c-9-dimethyl-BNO and its 3-epimer.These results are explained in terms of the conrotatory ring-closure of thermodynamically most favorable hydroxypentadienyl cation intermediates. 3-Methoxycarbonyl-cis-1,9-dimethyl-BNO produced from 4-methoxycarbonyl-2-methylcyclohexanone and 3-butyn-2-ol was successfully transformed into dl-nootkatone by converting the methoxycarbonyl group into isopropenyl of correct stereochemistry followed by ring enlargement.Cyclopentannulation using propargyl alcohol dianion adducts of 2-cycloalkenones is discussed.Annulation takes place regioselectively to give conjugated dienones, e.g., (E)-bicyclopentadeca-1(12),2-dien-13-one from 2-cyclododecenone.This product is led to dl-muscopyridine by conjugate 1,6-addition of methyl group followed by ring expansion and finally by aromatization with hydroxylamine hydrochloride.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 70219-46-4