70220-95-0Relevant academic research and scientific papers
Convenient annulation of bicyclo[6.3.0]undecanes
Lee, Kwangho,Kun Cha, Jin
, p. 6019 - 6021 (2001)
A facile, albeit nonstereoselective, method for the construction of a bicyclo[6.3.0]undecane skeleton has been developed by sequential application of the Suárez cleavage and 5-exo radical cyclization on the readily available [4+3] cycloadducts of cyclic oxyallyls.
79. Nucleophilic Addition to C,C-Double Bonds. IV. Ether Formation by Intramolecular Addition to Unsymmetrically Alkyl-substituted C,C-Double Bonds
Tombo, Gerardo M. Ramos,Pfund, Rolland A.,Ganter, Camille
, p. 813 - 822 (1981)
Tricyclic olefinic alcohols containing an unsymmetrically alkyl-substituted C,C-double bond were cyclized intramolecularly to their corresponding ethers under basic conditions: 9 -> 12, 10 -> 17 +18, and 11 -> 12 (Scheme 3, Table 1).The reactivity is mainly due to relieve of ground state strain.Alcohol 9 (endocyclic double bond) isomerized under intramolecular assistance by the hydroxyl group to 11 (exocyclic double bond) before cyclization to 12 occured (Scheme 5).The latter step being the faster one, no isomerization 11 -> 9 was observed.
Design and synthesis of a new tricyclic scaffold for molecular recognition
Caycho, Juana Robles,Garcia-Tellado, Fernando,De Armas, Pedro,Marrero-Tellado, Jose Juan
, p. 7911 - 7912 (2007/10/03)
The design of a novel family of tricyclic scaffolds for use in molecular recognition is described. The synthesis of the most simple member of this family is presented and its use exemplified in the synthesis of receptor 2.
