70249-94-4

Upstream product

• 3619-22-5 p-toluic hydrazide 

Downstream Products

• 1402046-33-6 2-[4-[(4-methoxybenzyl)amino]-3-(4-methylphenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetohydrazide 
• 1402046-32-5 {4-[(4-methoxybenzyl)amino]-3-(4-methylphenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl}acetate 
• 1402046-29-0 2-(2-hydroxyethyl)-5-(4-methylphenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 1402046-28-9 2-(2-hydroxyethyl)-5-(4-methylphenyl)-4-[(pyridin-2-ylmethyl)amino]-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 1402046-27-8 2-(2-hydroxyethyl)-4-benzylamino-5-(4-methylphenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 1402046-25-6 [4-benzylamino-3-(4-methylphfenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetic acid 
• 1402046-26-7 4-[(2-furylmethyl)amino]-2-(2-hydroxyethyl)-5-(4-methylphenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 1402046-24-5 [4-[(2-furylmethyl)amino]-3-(4-methylphenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazo-1-yl]acetic acid 
• 1379114-38-1 2-(2-hydroxyethyl)-4-[(4-methoxybenzyl)amino]-5-(4-methylphenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 1402046-23-4 [4-[(4-methoxybenzyl)amino]-3-(4-methylphenyl)-5-oxo-4,5-dihidro-1H-1,2,4-triazol-1-yl]acetic acid 
• 1402046-22-3 ethyl (3-(4-methylphenyl)-5-oxo-4-{[pyridin-4-ylmethylene]amino}-4,5-dihydro-1H-1,2,4-triazol-1-yl) acetate 
• 1402046-20-1 C₂₀H₂₀N₄O₃ 
• 1402046-19-8 ethyl (3-(4-methylphenyl)-5-oxo-4-{[2-furylmethylene]amino}-4,5-dihydro-1H-1,2,4-triazol-1-il) acetate 
• 1402046-18-7 ethyl [4-{[(4-methoxyphenyl)methylene]amino}-3-(4-metylphenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetate 

Relevant academic research and scientific papers

Carbon oxysulphide: A novel reagent for the synthesis of 4-amino/anilino-3-aryl/aryloxymethyl/thiophenoxymethyl-1,2,4-triazolin-5-ones and 5-arylamino-2-mercapto-1,3,4-oxadiazoles

Acid hydrazides 1 on reaction with carbon oxysulphide in the presence of alcoholic KOH afford potassium β-acylthiocarbazinates 2 which on further reaction with hydrazine hydrate or phenylhydrazine give 4-amino-3-substituted-1,2,4-triazolin-5-ones 3 and 4-amilino-3-substituted-1,2,4-triazolin-5-ones 5 respectively. 4-Substituted thiosemicarbazides 6 on treatment with carbon oxysulphide in the presence of ale NaOH afford sodium β-(N-arylthiocarbamyl)thiocarbazinates 7 which on cyclisation in the presence of ethanolic NaOH afford 5-arylamino-2-mercapto-1,3,4-oxadiazoles 8. On reaction with benzyl chloride in the presence of NaOH 8 isomerise to 3-benzylmercapto-4-substituted-1,2,4-triazolin-5-ones 9.