702670-02-8

Basic information

• Product Name: 6-[(4-chlorophenyl)methyl]-7-hydroxy-5-methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
• Synonyms: 6-[(4-chlorophenyl)methyl]-7-hydroxy-5-methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
• CAS NO: 702670-02-8
• Molecular Weight: 317.732
• Mol File: 702670-02-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6-[(4-chlorophenyl)methyl]-7-hydroxy-5-methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-[(4-chlorophenyl)methyl]-7-hydroxy-5-methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid(702670-02-8)
• EPA Substance Registry System: 6-[(4-chlorophenyl)methyl]-7-hydroxy-5-methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid(702670-02-8)

Safety Data

• Hazardous Substances Data: 702670-02-8(Hazardous Substances Data)

Upstream product

• 1310199-31-5 ethyl 6-[(4-chlorophenyl)methyl]-7-hydroxy-5-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate 
• 36600-72-3 ethyl 2-[(4-chlorophenyl)methyl]-3-oxobutanoate 
• 622-95-7 4-chlorobenzyl bromide 

Downstream Products

• 1370227-06-7 6-[(4-chlorophenyl)methyl]-7-hydroxy-5-methyl-N-[(2R)-oxolan-2-ylmethyl]pyrazolo-[1,5-a]pyrimidine-3-carboxamide 

Relevant articles and documents

TELOMERASE REVERSE TRANSCRIPTASE DEGRADERS AND METHODS OF USE THEREOF

The present disclosure provides TERT inhibitor compounds, a TERT inhibitor linked to a ubiquitin ligase ligand, as well as pharmaceutical compositions thereof. The present disclosure also provides methods of inhibiting telomerase reverse transcriptase (TERT) and methods of treating or preventing a disease or disorder using said compounds and/or compositions.

7-HYDROXY-PYRAZOLO[1,5-A] PYRIMIDINE COMPOUNDS AND THEIR USE AS CCR2 RECEPTOR ANTAGONISTS

The compounds of formula (I) are antagonists of the CCR2 receptor Wherein R1-7 and A are as defined in the claims.