70276-78-7

Upstream product

• 128381-65-7 5-Azido-2-<2-(4-methylphenyl)>-4-trifluormethylthiazol 
• 57014-96-7 4-(p-Tolyl)-2,2-bis(trifluormethyl)-2H-1,3-thiazet 
• 57015-06-2 4-methyl-N-(2,2,2-trifluoro-1-trifluoromethyl-ethylidene)-thiobenzamide 
• 70276-67-4 5-Fluor-2-(4-methylphenyl)-4-(trifluoromethyl)thiazol 

Relevant academic research and scientific papers

Introduction of Amino Groups Adjacent to Trifluoromethyl Groups in Heterocyclic Compounds; Synthesis of 5-Amino-4-trifluoromethylthiazoles

On reaction of 5-fluoro-4-trifluoromethylthiazoles 5 with primary aromatic and heteroaromatic amines, in the presence of 4-dimethylaminopyridine, a transamination process occurs to yield 5-amino-4-trifluoromethylthiazoles 2.Likewise, compounds 2 are forme

Reaction Behaviour of Trifluoromethyl Groups. Synthesis of 1,3-Azoles from Trifluoromethyl-substituted Hetero-1,3-dienes

4,4-Bis(trifluoromethyl)-substituted 1-oxa-3-aza-1,3-butadienes 1, 1-thia-3-aza-1,3-butadienes 2 as well as 1,3-diaza-1,3-butadienes 3 on heating with tin(II) chloride yield 5-fluoro-4-trifluoromethyl-substituted oxazoles 4, thiazoles 5, and imidazoles 6,