70303-65-0

Basic information

• Product Name: 3-ethyl-3-(3-hydroxy-4-methoxyphenyl)piperidine-2,6-dione
• Synonyms: 2,6-Piperidinedione, 3-ethyl-3-(3-hydroxy-4-methoxyphenyl)-
• CAS NO: 70303-65-0
• Molecular Formula: C₁₄H₁₇NO₄
• Molecular Weight: 263.2891
• Mol File: 70303-65-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 481.3°C at 760 mmHg
• Flash Point: 244.9°C
• Density: 1.207g/cm³
• Vapor Pressure: 6.87E-10mmHg at 25°C
• Refractive Index: 1.544
• CAS DataBase Reference: 3-ethyl-3-(3-hydroxy-4-methoxyphenyl)piperidine-2,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ethyl-3-(3-hydroxy-4-methoxyphenyl)piperidine-2,6-dione(70303-65-0)
• EPA Substance Registry System: 3-ethyl-3-(3-hydroxy-4-methoxyphenyl)piperidine-2,6-dione(70303-65-0)

Safety Data

• Hazardous Substances Data: 70303-65-0(Hazardous Substances Data)

Relevant articles and documents

Identification and synthesis of a methylated catechol metabolite of glutethimide isolated from biological fluids of overdose victims

Urine samples from victims severely intoxicated by glutethimide were hydrolyzed enzymatically. TLC, GLC, and mass spectral analyses revealed a methylated catechol metabolite of the parent drug. Two synthetic pathways are described for the preparation of 2-ethyl-2-(3-methoxy-4-hydroxyphenyl)glutarimide and 2-ethyl-2-(3-hydroxy-4-methoxyphenyl)glutarimide. Comparisons of GLC and mass spectral data to a compound isolated from the body fluids of glutethimide overdose victims conclusively identified a new 3-methoxy-4-hydroxyphenyl metabolite of glutethimide in humans.