7031-27-8

Basic information

• Product Name: (PHENYLTHIO)ACETYL CHLORIDE
• Synonyms: (PHENYLTHIO)ACETYL CHLORIDE;THIOPHENOXYACETYL CHLORIDE;2-(PHENYLTHIO)ACETYL CHLORIDE, TECH.;2-(phenylthio)acetyl chloride;(Phenylthio)acetyl chloride 97%
• CAS NO: 7031-27-8
• Molecular Formula: C₈H₇ClOS
• Molecular Weight: 186.66
• Mol File: 7031-27-8.mol
• Article Data: 33

Chemical Properties

• Boiling Point: 253.5°C at 760 mmHg
• Flash Point: >230 °F
• Appearance: /
• Density: 1.258 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0182mmHg at 25°C
• Refractive Index: n20/D 1.5825(lit.)
• CAS DataBase Reference: (PHENYLTHIO)ACETYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (PHENYLTHIO)ACETYL CHLORIDE(7031-27-8)
• EPA Substance Registry System: (PHENYLTHIO)ACETYL CHLORIDE(7031-27-8)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-27-36/37/39-45
• RIDADR: UN 3265 8/PG 2
• WGK Germany: 3
• Hazardous Substances Data: 7031-27-8(Hazardous Substances Data)

Usage

General Description

(Phenylthio)acetyl chloride is an acid halide. It participates in the Friedel -Crafts acylation of arenes to afford α-sulfenylated acetophenones.

InChI:InChI=1/C8H7ClOS/c9-8(10)6-11-7-4-2-1-3-5-7/h1-5H,6H2

Upstream product

• 103-04-8 (phenylthio)acetic acid 
• 108-98-5 thiophenol 
• 79-04-9 chloroacetyl chloride 
• 7605-25-6 ethyl phenylsulfenylacetate 

Downstream Products

• 101584-03-6 phenylsulfanyl-acetic acid-((S)-1-methyl-2-phenyl-ethylamide) 
• 102476-53-9 (+/-)-phenylsulfanyl-acetic acid-(1,2t,5c-trimethyl-4-phenyl-[4r]piperidyl ester) 
• 122657-58-3 2-furyl phenylthiomethyl ketone 
• 55834-30-5 7-(phenylthio)bicyclo[3.2.0]hept-2-en-6-one 
• 77705-59-0 2-(2-(phenylthio)acetamido)benzoic acid 
• 99563-90-3 2-methyl-2-<(phenylthio)acetoxy>propanenitrile 
• 36734-50-6 1‐(4‐methylphenyl)‐2‐(phenylsulfanyl)ethanone 
• 63006-68-8 tert-butyl (phenylthio)acetate 
• 130-03-0 thioindoxyl 
• 16222-10-9 1-phenyl-2-(phenylthio)ethanone 
• 17698-56-5 Benzolsulfinylessigsaeure-<4-nitro-anilid> 
• 17531-00-9 Benzolsulfinylessigsaeure-<3-chlor-anilid> 
• 1778-09-2 4-(Methylthio)acetophenone 
• 25907-38-4 ethyl 4-(phenylthio)-acetoacetate 

Relevant articles and documents

N-(2-hydroxy-5-chlorophenyl)thiophenyl-acetamide

In molecules of the title compound, C14H12ClNO2S, the phenylthio group and the remainder of the heavyatom skeleton form two different planes which are nearly perpendicular to each other. The molecules are interlinked by O-

Synthesis of and characterization of some Heterocyclic Compounds derived from Thiophenol

This research work involved preparation of heterogeneous pent lateral cyclic compounds (thiazolidine -4- one, benzothiazole, triazole, 4-oxothiazolidin) using thiophenol as raw materials: Thiophenol was reacted with mono chloroacetic acid in the presence of potassium hydroxide to prepare (sh1) followed by ortho amino aniline results the (sh2). The reaction of thiophenol with ethylchloroacetate afforded (sh3) and the reaction of (sh3) with thiosemicarbazide and 4% NaOH leads to ring closure giving 1,2,4- triazole (sh5). A treatment of thiophenol with hydrazine hydrate to obtain the intermediate (sh6) with aromatic aldehyde synthesized azomethines (sh7- sh9) then treated with mercaptoacetic acid to obtained (sh10-sh12). A treatment of thiophenol with chloroacetyl chloride produced (sh13) compound then treated with hydrazine hydrate to obtain (sh14) compound followed by bromobenzaldehyde synthesized azomethine (sh15) compound then treated with mercaptoacetic acid to obtained (sh16) compound. Characterization results for the prepared compounds using IR spectroscopy, NMR and melting points confirmed their chemical structures.

Oxidized Hemithioindigo Photoswitches—Influence of Oxidation State on (Photo)physical and Photochemical Properties

The photophysical and photochemical properties of sulfoxide and sulfone derivatives of hemithioindigo photoswitches are scrutinized and compared to the unoxidized parent chromophores. Oxidation results in significantly blue-shifted absorptions and mostly