70311-77-2Relevant academic research and scientific papers
Pyrimidopyridazines. 3. Preferential Formation of 8-Amino-1H-pyrimido-1,2-diazepin-6(7H)-ones by Cyclizations with α,γ-Diketo Esters
Mallory, W. Revill,Morrison, Robert W.,Styles, Virgil L.
, p. 667 - 674 (2007/10/02)
6-(1-Methylhydrazino)isocytosine cyclizes with α,γ-diketo esters to give pyrimidopyridazines and 1H-pyrimido-1,2-diazepines, the latter being predominant in each case.The pyrimidodiazepines are susceptible to ring-opening/ring-closure rearra
1H-Pyrimido[4,5-c]-1,2-diazepines
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, (2008/06/13)
Compounds of the general formula (I) STR1 wherein R1 and R2 are selected from a lower alkyl group, a phenyl group (optionally substituted by one or more hydroxy or lower alkoxy groups), a pyridyl group or a group --CO2 R where R is a lower alkyl group, (provided that when R1 is a group --CO2 R, R2 is a lower alkyl group) are disclosed. The compounds of formula (I) are useful as intermediates to compounds of other ring systems which are of pharmacological interest. Certain of the compounds of formula (I) are also useful as antimicrobial agents.
